Protein Alignment CG14605 and Slc2a8

DIOPT Version :10

• Sequence 1: NP_649707.3
• Gene: CG14605 / 40867
• FlyBaseID: FBgn0037486
• Length: 432
• Species: Drosophila melanogaster
• Sequence 2: NP_445946.2
• Gene: Slc2a8 / 85256
• RGDID: 620611
• Length: 478
• Species: Rattus norvegicus
• Alignment Length: 465
• Identity: 114/465 - (24%)
• Similarity: 213/465 - (45%)
• Gaps: 67/465 - (14%)

  Fly     3 LTHGISLGWFSPTLPTLISDNSPIGHPIDISEVKWIGASFGIGCLICNMVICVPVSYFGIKKCMY 67
            |:.|.:||:.||.:|:| ...:|....:..:...|.||...:|.....::....:...|.|..:.
  Rat    38 LSFGFALGYSSPAIPSL-RRTAPPALRLGDTAASWFGAVVTLGAAAGGVLGGWLLDRAGRKLSLL 101

  Fly    68 FVPLPNILNWVLIYFASKSLYFYVCRVLLGISGGTLVVCFPVFIAEVSDNSVRGTLGSFFMMTLC 132
            ...:|.:..:.:|..|.........|:|.|::.|...:..||:|:|::..:|||.|||...:.:.
  Rat   102 LCTVPFVTGFAVITAARDVWMLLGGRLLTGLACGVASLVAPVYISEIAYPAVRGLLGSCVQLMVV 166

  Fly   133 SGITVGFVLVYCLSYH---VLPCVVIFLPILYLCLIIPLPEPPQDLLKRGHEEKAEKSFCFY--- 191
            :||.:.:|..:.|.:.   ||.||.   |.|.|.|:..:||.|:.||.:...::|..:..|.
  Rat   167 TGILLAYVAGWVLEWRWLAVLGCVP---PTLMLLLMCYMPETPRFLLTQHQYQEAMAALRFLWGS 228

  Fly   192 -KNLSKDPAQQDDNKAEFDKLR----NKVLASGIAEKITPADFFNKVSGKAFGLIAVLLLSNQMS 251
             :...:.|...:....:...||    :|.|..||.                      |::..|:|
  Rat   229 EEGWEEPPVGAEHQGFQLAMLRRPGVHKPLIIGIC----------------------LMVFQQLS 271

  Fly   252 GSFAIFNYSSTIFEQLGSRMEPNLCGIFLGVVQIFGLISAVLLVDRVGRRLLL-------IPSLA 309
            |..||..|::||||:...: :.:|..:.:|::|:.....|.|::||.||:|||       :.|::
  Rat   272 GVNAIMFYANTIFEEAKFK-DSSLASVTVGIIQVLFTAVAALIMDRAGRKLLLALSGVIMVFSMS 335

  Fly   310 GMG----LAELG------VGLLKSFASQ--DFLHNNGWIALTLMGIVSFTASAGIVALTFVIIVE 362
            ..|    |.:.|      ||||...:::  |......|:|:..|.:.....:.|...:.::::.|
  Rat   336 AFGTYFKLTQSGPSNSSHVGLLVPISAEPADVHLGLAWLAVGSMCLFIAGFAVGWGPIPWLLMSE 400

  Fly   363 LLPFKIRAPGISISMCGLSLSVFIALITYPV-----LINDYGVHVTMFVSASFCLLGLVVLGIFL 422
            :.|..|:  |::..:|.|:......|:|...     ::..||   ..:::|:||:|.::....|:
  Rat   401 IFPLHIK--GVATGVCVLTNWFMAFLVTKEFNSIMEILRPYG---AFWLTAAFCILSVLFTLTFV 460

  Fly   423 PETRGKSITQ 432
            |||:|:::.|
  Rat   461 PETKGRTLEQ 470

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14605	NP_649707.3	MFS	1..432	CDD:475125	113/463 (24%)
Slc2a8	NP_445946.2	Dileucine internalization motif. /evidence=ECO:0000269|PubMed:10671487	12..13
		MFS	27..470	CDD:475125	113/463 (24%)