Protein Alignment CG14605 and ITR1

DIOPT Version :10

• Sequence 1: NP_649707.3
• Gene: CG14605 / 40867
• FlyBaseID: FBgn0037486
• Length: 432
• Species: Drosophila melanogaster
• Sequence 2: NP_010785.1
• Gene: ITR1 / 852108
• SGDID: S000002905
• Length: 584
• Species: Saccharomyces cerevisiae
• Alignment Length: 476
• Identity: 103/476 - (21%)
• Similarity: 182/476 - (38%)
• Gaps: 84/476 - (17%)

  Fly     6 GISLGWFSPTLPTLISDNSPIGHPI-DISEVKWIGASFGIGCLICNMVICVPVSYFGIKKCMYFV 69
            |...|:.|   ..|||..:.:.|.: ...|.:.:.|:..:|.||.::........||.|:|:...
Yeast   101 GYDTGYIS---SALISIGTDLDHKVLTYGEKEIVTAATSLGALITSIFAGTAADIFGRKRCLMGS 162

  Fly    70 PLPNILNWVLIYFASKSLYFYVCRVLLGISGGTLVVCFPVFIAEVSDNSVRGTLGSFFMMTLCSG 134
            .|..::..:|...|.......|.|:::|...|...:..|:||:|::...:||.|.....:.|..|
Yeast   163 NLMFVIGAILQVSAHTFWQMAVGRLIMGFGVGIGSLIAPLFISEIAPKMIRGRLTVINSLWLTGG 227

  Fly   135 ITVGFVLVYCLSY-----------HVLPCVVIFLPILYLCLIIPLPEPPQ------------DLL 176
            ..|.:.....|:|           .::|..|.|     .||.. ||:.|:            ::|
Yeast   228 QLVAYGCGAGLNYVNNGWRILVGLSLIPTAVQF-----TCLCF-LPDTPRYYVMKGDLARATEVL 286

  Fly   177 KRGHEEKAEKSFCFYKNLSKDPAQQDDNKAEFDKLRNKVLASGIAEKI---------TPADFFNK 232
            ||.:.:.:|:..             :....|...|...:....:.||:         .|::....
Yeast   287 KRSYTDTSEEII-------------ERKVEELVTLNQSIPGKNVPEKVWNTIKELHTVPSNLRAL 338

  Fly   233 VSGKAFGLIAVLLLSNQMSGSFAIFNYSSTIFEQLGSRMEPNLCGIFLGVVQIFGLISAVLLVDR 297
            :.|  .||.|:    .|.:|..::..:|.||||.:|.:....:..|..|...||.|: |...:|:
Yeast   339 IIG--CGLQAI----QQFTGWNSLMYFSGTIFETVGFKNSSAVSIIVSGTNFIFTLV-AFFSIDK 396

  Fly   298 VGRRLLLIPSLAGMGLAELGVGLLKSFASQDFLHNNGWIALTLMGIVSFTASAGIVALTFVIIV- 361
            :|||.:|:..|.||.:|.:...:...|....|   :|.:|:.   :.|..:|.|||.:.|:|:.
Yeast   397 IGRRTILLIGLPGMTMALVVCSIAFHFLGIKF---DGAVAVV---VSSGFSSWGIVIIVFIIVFA 455

  Fly   362 ---------------ELLPFKIRAPGISISMCGLSLSVFIALITYPVLINDYGVHVTMFVSASFC 411
                           ||.|..:|..|.|.:.........:...|:..::.:.....|....|...
Yeast   456 AFYALGIGTVPWQQSELFPQNVRGIGTSYATATNWAGSLVIASTFLTMLQNITPAGTFAFFAGLS 520

  Fly   412 LLGLVVLGIFLPETRGKSITQ 432
            .|..:......||..|..:.:
Yeast   521 CLSTIFCYFCYPELSGLELEE 541

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14605	NP_649707.3	MFS	1..432	CDD:475125	103/474 (22%)
ITR1	NP_010785.1	MFS_HMIT_like	92..533	CDD:340918	100/466 (21%)