Protein Alignment CG14605 and SLC2A10

DIOPT Version :10

• Sequence 1: NP_649707.3
• Gene: CG14605 / 40867
• FlyBaseID: FBgn0037486
• Length: 432
• Species: Drosophila melanogaster
• Sequence 2: XP_011527362.1
• Gene: SLC2A10 / 81031
• HGNCID: 13444
• Length: 562
• Species: Homo sapiens
• Alignment Length: 543
• Identity: 118/543 - (21%)
• Similarity: 203/543 - (37%)
• Gaps: 168/543 - (30%)

  Fly     3 LTHGISLGWFSPTLPTLISDNSPIGHPIDISEVKWIGASFGIGCLICNMVICVPVSYFGIKKCMY 67
            ||.|..|...|..|..|..|     ..:...|.:::..|..:|.|:.::|....:..:|.|:.:.
Human    41 LTFGYELAVISGALLPLQLD-----FGLSCLEQEFLVGSLLLGALLASLVGGFLIDCYGRKQAIL 100

  Fly    68 FVPLPNILNWVLIYFASKSLYFYVCRVLLG--ISGGTLVVCFPVFIAEVSDNSVRGTLGSFFMMT 130
            ...|..:...:.:..|....:..:.|.::|  ||..::..|  ::::|:.....||.|.|.:.
Human   101 GSNLVLLAGSLTLGLAGSLAWLVLGRAVVGFAISLSSMACC--IYVSELVGPRQRGVLVSLYE-- 161

  Fly   131 LCSGITVGFVLVYCLSY----------HVL-----PCVVIFLPILYLCLIIPLPEPPQDLLKRGH 180
              :|||||.:|.|.|:|          |:.     |.|:..|.:|:|
Human   162 --AGITVGILLSYALNYALAGTPWGWRHMFGWATAPAVLQSLSLLFL------------------ 206

  Fly   181 EEKAEKSFCFYKNLSKDPAQQDDNKAEFDKLRNKVLASGIAEKITPA-------DFF---NKVSG 235
                             ||..|:.....|.:   .|..|.|.|:.|.       |.|   :.:.|
Human   207 -----------------PAGTDETATHKDLI---PLQGGEAPKLGPGRPRYSFLDLFRARDNMRG 251

  Fly   236 K-AFGLIAVLLLSNQMSGSFAIFNYSSTIFEQLG--SRMEPNLCGIFLGVVQIFGLISAVLLVDR 297
            : ..||  .|:|..|::|...:..|:||||..:|  ......|..:.||.|::...::|:.||||
Human   252 RTTVGL--GLVLFQQLTGQPNVLCYASTIFSSVGFHGGSSAVLASVGLGAVKVAATLTAMGLVDR 314

  Fly   298 VGRRLLLIPSLAGMGLAELGVGLLKSFA-----------------------SQDFLHNNG----- 334
            .|||.||:...|.|.|:..|:||: |||                       ....|.::.
Human   315 AGRRALLLAGCALMALSVSGIGLV-SFAVPMDSGPSCLAVPNATGQTGLPGDSGLLQDSSLPPIP 378

  Fly   335 ----------------------------------------------------WIALTLMGIVSFT 347
                                                                |.||..:.:....
Human   379 RTNEDQREPILSTAKKTKPHPRSGDPSAPPRLALSSALPGPPLPARGHALLRWTALLCLMVFVSA 443

  Fly   348 ASAGIVALTFVIIVELLPFKIRAPGISISMC---GLSLSVFIALITYPVLINDYGVHVTMFVSAS 409
            .|.|...:|::::.|:.|.:||  |.:.:.|   ..:.::||:| ::..||...|:..|..:...
Human   444 FSFGFGPVTWLVLSEIYPVEIR--GRAFAFCNSFNWAANLFISL-SFLDLIGTIGLSWTFLLYGL 505

  Fly   410 FCLLGLVVLGIFLPETRGKSITQ 432
            ..:|||..:.:|:|||:|:|:.:
Human   506 TAVLGLGFIYLFVPETKGQSLAE 528

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14605	NP_649707.3	MFS	1..432	CDD:475125	118/541 (22%)
SLC2A10	XP_011527362.1	MFS_GLUT10_Class3	31..529	CDD:340994	118/543 (22%)