Protein Alignment CG14605 and SLC2A5

DIOPT Version :10

• Sequence 1: NP_649707.3
• Gene: CG14605 / 40867
• FlyBaseID: FBgn0037486
• Length: 432
• Species: Drosophila melanogaster
• Sequence 2: NP_003030.1
• Gene: SLC2A5 / 6518
• HGNCID: 11010
• Length: 501
• Species: Homo sapiens
• Alignment Length: 424
• Identity: 102/424 - (24%)
• Similarity: 187/424 - (44%)
• Gaps: 64/424 - (15%)

  Fly    42 FGIGCLICNMVICVPVSYFGIKKCMYFVPLPNILNWVLIYFASKSLYF---YVCRVLLGISGGTL 103
            |..|..|.::::...|:.||.|..:.|..:.:|:..:|:..:..:..|   .:.|:|:||..|..
Human    78 FPFGGFIGSLLVGPLVNKFGRKGALLFNNIFSIVPAILMGCSRVATSFELIIISRLLVGICAGVS 142

  Fly   104 VVCFPVFIAEVSDNSVRGTLG---SFFMMTLCSGITVGFVLVYCLSYHVLPCVVIFLPIL----- 160
            ....|:::.|::..::||.||   ..|       ||||.::........|...|...|||
Human   143 SNVVPMYLGELAPKNLRGALGVVPQLF-------ITVGILVAQIFGLRNLLANVDGWPILLGLTG 200

  Fly   161 ----YLCLIIP-LPEPPQDLLKRGHEEKAEKSFCFYKNLSKDPAQQ-----DDNKAEFDKLRNKV 215
                ...|::| .||.|:.||.:..:|.|.|.           |.|     |....|..::|.:.
Human   201 VPAALQLLLLPFFPESPRYLLIQKKDEAAAKK-----------ALQTLRGWDSVDREVAEIRQED 254

  Fly   216 LASGIAEKITPADFFNKVSGKAFGLIAVLLL--SNQMSGSFAIFNYSSTIFEQLG---SRMEPNL 275
            .|...|..|:....| ::....:.|:::::|  ..|:||..||:.|:..|:...|   ..::...
Human   255 EAEKAAGFISVLKLF-RMRSLRWQLLSIIVLMGGQQLSGVNAIYYYADQIYLSAGVPEEHVQYVT 318

  Fly   276 CGIFLGVVQIFGLISAVLLVDRVGRRLLLIPSLAGMGLAELGVGLL-KSFASQDFLHNNGWIA-L 338
            .|  .|.|.:.....||.:|:.:||||||   |.|..:..:...:| .:.|.||.:   .|:. :
Human   319 AG--TGAVNVVMTFCAVFVVELLGRRLLL---LLGFSICLIACCVLTAALALQDTV---SWMPYI 375

  Fly   339 TLMGIVSFTA--SAGIVALTFVIIVELLPFKIRAPGISISMCGLS---LSVFIALITYPVLINDY 398
            :::.::|:..  :.|...:..::|.|:.   :::...|..|.|.|   ||.|...:.:|.:....
Human   376 SIVCVISYVIGHALGPSPIPALLITEIF---LQSSRPSAFMVGGSVHWLSNFTVGLIFPFIQEGL 437

  Fly   399 GVHVTMFVSASFCLLGLVVLGIFLPETRGKSITQ 432
            |.: :..|.|..|||..:.:.:.:|||:.|:..:
Human   438 GPY-SFIVFAVICLLTTIYIFLIVPETKAKTFIE 470

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14605	NP_649707.3	MFS	1..432	CDD:475125	102/422 (24%)
SLC2A5	NP_003030.1	MFS_GLUT_Class2	23..471	CDD:340990	102/424 (24%)