Protein Alignment CG14605 and SLC2A2

DIOPT Version :10

• Sequence 1: NP_649707.3
• Gene: CG14605 / 40867
• FlyBaseID: FBgn0037486
• Length: 432
• Species: Drosophila melanogaster
• Sequence 2: NP_000331.1
• Gene: SLC2A2 / 6514
• HGNCID: 11006
• Length: 524
• Species: Homo sapiens
• Alignment Length: 466
• Identity: 111/466 - (23%)
• Similarity: 200/466 - (42%)
• Gaps: 87/466 - (18%)

  Fly    16 LPTLISDNSPIGHPIDISEVKWIGA-------------SFGIGCLICNMVICVPVSYFG------ 61
            |||:....:|  .|...:|.:.:.|             ||.:|.:        ..|:||
Human    67 LPTISYSMNP--KPTPWAEEETVAAAQLITMLWSLSVSSFAVGGM--------TASFFGGWLGDT 121

  Fly    62 ---IKKCMYFVPLPNILNWV--------------LIYFASKSLYFYVCRVLLGISGGTLVVCFPV 109
               ||..:    :.|||:.|              ::..|.:|:....|.::.|:        .|:
Human   122 LGRIKAML----VANILSLVGALLMGFSKLGPSHILIIAGRSISGLYCGLISGL--------VPM 174

  Fly   110 FIAEVSDNSVRGTLGSFFMMTLCSGITVG------FVLVYCLSYHVLPCVVIFLPILYLCLIIPL 168
            :|.|::..::||.||:|..:.:.:||.:.      |:|.....:|:|..:.....||...|:...
Human   175 YIGEIAPTALRGALGTFHQLAIVTGILISQIIGLEFILGNYDLWHILLGLSGVRAILQSLLLFFC 239

  Fly   169 PEPPQDL-LKRGHEEKAEKSFCFYKNLSKDPAQQDDNKAEFDKLRNKVLASGIAEKITPADFFNK 232
            ||.|:.| :|...|.||::|.       |.....||...:.:::|.:...:...:|::....|..
Human   240 PESPRYLYIKLDEEVKAKQSL-------KRLRGYDDVTKDINEMRKEREEASSEQKVSIIQLFTN 297

  Fly   233 VSGKAFGLIAVLL-LSNQMSGSFAIFNYSSTIFEQLGSRMEPNLCGIFLGVVQIFGLISAVLLVD 296
            .|.:...|:|::| ::.|.||...||.||::||:..|. .:|....|.:|.|.:.....:|.||:
Human   298 SSYRQPILVALMLHVAQQFSGINGIFYYSTSIFQTAGI-SKPVYATIGVGAVNMVFTAVSVFLVE 361

  Fly   297 RVGRRLLLIPSLAGMGLA----ELGVGLLKSFASQDFLHNNGWIALTLMGIVSFTASAGIVALTF 357
            :.|||.|.:..::||.:.    .:|:.||..|:...::   ..||:.|  .||| ...|...:.:
Human   362 KAGRRSLFLIGMSGMFVCAIFMSVGLVLLNKFSWMSYV---SMIAIFL--FVSF-FEIGPGPIPW 420

  Fly   358 VIIVELLPFKIRAPGISISMCGLSLSVFIALITYPVLINDYGVHVTMFVSASFCLLGLVVLGIF- 421
            .::.|......|...::|:........||..:.:..:.:..|.:| .|:.|. .||...:...|
Human   421 FMVAEFFSQGPRPAALAIAAFSNWTCNFIVALCFQYIADFCGPYV-FFLFAG-VLLAFTLFTFFK 483

  Fly   422 LPETRGKSITQ 432
            :|||:|||..:
Human   484 VPETKGKSFEE 494

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14605	NP_649707.3	MFS	1..432	CDD:475125	111/464 (24%)
SLC2A2	NP_000331.1	MFS_GLUT_Class1	12..490	CDD:340989	108/460 (23%)