Protein Alignment CG14605 and SLC2A9

DIOPT Version :10

• Sequence 1: NP_649707.3
• Gene: CG14605 / 40867
• FlyBaseID: FBgn0037486
• Length: 432
• Species: Drosophila melanogaster
• Sequence 2: XP_011512158.1
• Gene: SLC2A9 / 56606
• HGNCID: 13446
• Length: 615
• Species: Homo sapiens
• Alignment Length: 438
• Identity: 103/438 - (23%)
• Similarity: 182/438 - (41%)
• Gaps: 85/438 - (19%)

  Fly    27 GHPIDISEVKWIG----ASFGIGCLICNMVICVPVSYFGIKKCMYFVPLPNILNWVLIYFASKSL 87
            |.|||...:..:.    :.|.||.|:..:::.:.....|.|..:    |.|  |.    ||..:.
Human    98 GRPIDPDTLTLLWSVTVSIFAIGGLVGTLIVKMIGKVLGRKHTL----LAN--NG----FAISAA 152

  Fly    88 YFYVC-------------RVLLGISGGTLVVCFPVFIAEVSDNSVRGTLGSFFMMTLCSGITVGF 139
            ....|             |.::||.||..:...|::::|:|...:||:||....:.:|.|:..|.
Human   153 LLMACSLQAGAFEMLIVGRFIMGIDGGVALSVLPMYLSEISPKEIRGSLGQVTAIFICIGVFTGQ 217

  Fly   140 VL------------VYCLSYHVLPCVVIFLPILYLCLIIPLPEPPQDLLKRGHEE-KAEKSFCFY 191
            :|            .|.....|:|.||..|.:.:      ||:.|:.||...|.| :|.|:|..:
Human   218 LLGLPELLGKESTWPYLFGVIVVPAVVQLLSLPF------LPDSPRYLLLEKHNEARAVKAFQTF 276

  Fly   192 KNLSK-DPAQQDDNKAEFDKLRNKVLASGIAEKI-TPADFFNKVSGKAFGLIAVLLLSNQMSGSF 254
              |.| |.:|:.:......:::..:....:.|.: .|...:..|:      :.|.:...|:.|..
Human   277 --LGKADVSQEVEEVLAESRVQRSIRLVSVLELLRAPYVRWQVVT------VIVTMACYQLCGLN 333

  Fly   255 AIFNYSSTIFEQLGSRMEP---NLCGIFLGVVQIFGLISAVLLVDRVGRRLLLIPSLAGMGLAEL 316
            ||:.|:::||.:.|  :.|   ....:..|.::....:.:.|:::.:|||.|||   .|.||..|
Human   334 AIWFYTNSIFGKAG--IPPAKIPYVTLSTGGIETLAAVFSGLVIEHLGRRPLLI---GGFGLMGL 393

  Fly   317 GVGLLK-SFASQDFLHNNGWIA-LTLMGIVSFTAS--AGIVALTFVIIVELLPFKIRAPGISISM 377
            ..|.|. :...||   :..|:. |:::||::..||  :|...:.|::..|......|.....|:.
Human   394 FFGTLTITLTLQD---HAPWVPYLSIVGILAIIASFCSGPGGIPFILTGEFFQQSQRPAAFIIAG 455

  Fly   378 CGLSLSVFIALITYPVLINDYGVHVTMFVSASFCLLGLVVL--GIFLP 423
            ....||.|...:.:|            |:.....||.|:.:  |..||
Human   456 TVNWLSNFAVGLLFP------------FIQLLLLLLSLLRIQPGFKLP 491

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14605	NP_649707.3	MFS	1..432	CDD:475125	103/438 (24%)
SLC2A9	XP_011512158.1	MFS_GLUT_Class2	59..466	CDD:340990	95/399 (24%)