DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14605 and CG6484

DIOPT Version :9

Sequence 1:	NP_649707.3	Gene:	CG14605 / 40867	FlyBaseID:	FBgn0037486	Length:	432	Species:	Drosophila melanogaster
Sequence 2:	NP_611234.1	Gene:	CG6484 / 36994	FlyBaseID:	FBgn0034247	Length:	465	Species:	Drosophila melanogaster

Alignment Length:	458	Identity:	126/458 - (27%)
Similarity:	221/458 - (48%)	Gaps:	58/458 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 SLTHGISLGWFSPTLPTLISDNSPIGHPIDISEVKWIGASFGIGCLICNMVICVPVSY----FGI 62
            :|..|.|:||.|| :..:|:.|:..|.||..|:..|:.:...:|.    .|||:|:.:    .|.
  Fly    20 ALCMGASIGWSSP-VENMITVNTEYGFPISSSQFGWVSSLLTLGA----TVICIPIGFAIDWIGR 79

  Fly    63 KKCMYFVPLPNILNWVLIYFASKSLYFYVCRVLLGISGGTLVVCFPVFIAEVSDNSVRGTLGSFF 127
            :..|..:..|.::.|||:.||......|..|.:||:.||...|..|::..|::..::|||:||||
  Fly    80 RPTMLALIPPYMVGWVLMLFAKNVTMLYFGRFILGMCGGAFCVTAPMYCTEITATALRGTIGSFF 144

  Fly   128 MMTLCSGITVGFVLVYCLSYHVLPCVVIFLPIL---YLCLIIP---------LPEPPQDLLKRGH 180
            .:.:.||:..|::            |..|||:|   .||.|:|         :||.|..|..:|.
  Fly   145 QLLIVSGVLYGYL------------VGAFLPLLTINILCAILPVIFAIIHFFMPESPVYLAMKGR 197

  Fly   181 EEKAEKSFCFYKNLSKDPAQQDDNKAEFDKLRNKV------LASGIAEKITPADFFNKVSGKAFG 239
            .:.|.|:..:.:  .||....|:.|...::.:.::      :.|.:...|..         |..|
  Fly   198 NDDAAKALQWLR--GKDADIDDELKEILEESQKQIDMPQVNILSSLRRPIVL---------KGLG 251

  Fly   240 LIAVLLLSNQMSGSFAIFNYSSTIFEQLGSRMEPNLCGIFLGVVQIFGLISAVLLVDRVGRRLLL 304
            :..:|.:..|.:|..|:..||::|||..||.:..:...:.:||.|:...:.||.::|:.|||:||
  Fly   252 IAVLLQVFQQWTGINAVLFYSASIFEDTGSDISGSDATLIIGVTQVTSTLVAVAIIDKAGRRILL 316

  Fly   305 IPS--LAGMGLAELGVGL-LKSF--ASQDFLHNNGWIALTLMGIVSFTASAGIVALTFVIIVELL 364
            :.|  |..:..|.:||.. ||..  ||.|   |.||:.::.:.|.....|.|...:.::::.||.
  Fly   317 LISGVLMAVSTALMGVYFQLKENDPASMD---NFGWLPISSICIFIIFFSIGFGPVPWLVMAELF 378

  Fly   365 PFKIRAPGISISMCGLSLSVFIALITYPVLINDYGVHVTMFVSASFCLLGLVVLGIFLPETRGKS 429
            ...:::...||:.....||.|:..:.:|:|.:..|...|.::..:..::.......|:|||:||:
  Fly   379 SEDVKSVAGSIAGTSNWLSAFVVTLLFPILKSSIGPGPTFWIFTAIAVIAFFYSLFFVPETKGKT 443

  Fly   430 ITQ 432
            |.:
  Fly   444 IIE 446

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14605	NP_649707.3	MFS	1..421	CDD:119392	119/445 (27%)
CG14605	NP_649707.3	MFS_1	1..387	CDD:284993	115/411 (28%)
CG6484	NP_611234.1	Sugar_tr	14..451	CDD:278511	126/458 (28%)
CG6484	NP_611234.1	MFS	14..436	CDD:119392	119/446 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45444296
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D430696at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR48021
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
	6	5.850