Protein Alignment CG14605 and hmit-1.2

DIOPT Version :10

• Sequence 1: NP_649707.3
• Gene: CG14605 / 40867
• FlyBaseID: FBgn0037486
• Length: 432
• Species: Drosophila melanogaster
• Sequence 2: NP_507624.1
• Gene: hmit-1.2 / 180206
• WormBaseID: WBGene00013074
• Length: 613
• Species: Caenorhabditis elegans
• Alignment Length: 555
• Identity: 120/555 - (21%)
• Similarity: 199/555 - (35%)
• Gaps: 179/555 - (32%)

  Fly     1 MSLTHGISL--GWFSPTLPTLISDNSPIGH-PIDISEVKWIGASFGIGCLICNMVICVPVSYFGI 62
            :|:|.|::.  .|||.      :.:...|. ||      .||::.   ..:|..|||.
 Worm    72 VSITPGMAAVGAWFSG------AGSDRYGRKPI------IIGSTL---IFVCGAVICA------- 114

  Fly    63 KKCMYFVPLPNILNWVLIYFASKSLYFYVCRVLLGISGGTLVVCFPVFIAEVSDNSVRGTLGSFF 127
                        :.|.       .:...:.|:.||:..|...:..||::.|.|...|||||.|.|
 Worm   115 ------------VAWT-------KIVMLIGRIFLGVGIGFASMVVPVYLGEASPTHVRGTLVSAF 160

  Fly   128 MMTLCSGITVGFVLVYCLSY---HVLPCVVIF----LPIL--YLCLIIPLPEPPQDLLKRGHEEK 183
            .|.:..|..|..::....||   :.:...::|    :|.|  ::|.|. |||.|:.|.:.||.|:
 Worm   161 AMMISFGQVVANIMGGVFSYWEPYTIGWRLMFAFAGIPALIQFVCFIF-LPETPRWLYENGHTEQ 224

  Fly   184 AEK----------SFCFYKNLS-KDPAQQDDNKAEFDKLRNKVLASGIAEKITPADFFNKVSGKA 237
            ||:          .:..|:... |..|::...:.|.:|....|:...:.   ||...      ||
 Worm   225 AEQVLEKIYGGNTEWIEYELAEIKTYAEERQKQMEEEKKSGPVIWRILK---TPHVL------KA 280

  Fly   238 FGLIAVLLLSNQMSGSFAIFNYSSTIFEQLGSRMEPNL--CGIFLGVVQIFGLISAVLLVDRVGR 300
            ..:.::|....|::|...|..|::.|....|......:  ..:.|.:..:.|..:.:..::::||
 Worm   281 CFIGSMLQAFQQLAGINTILYYTADIIRSAGIENYHTIIWISVILSICNLIGPFAPMFFIEKLGR 345

  Fly   301 RLLLIPSLAG--MGLAELGVGLL-------KSFASQDFL-------------------------- 330
            |.|.:.|.||  :.|..:||..|       .:|....:|
 Worm   346 RKLFLFSCAGVVVSLVLIGVSFLLVGNDSAPNFDRSAYLLAGNYQSNGEAESCLMLSNCDSCVTS 410

  Fly   331 --------------------HN------------NG---------------W-----------IA 337
                                ||            ||               |           :.
 Worm   411 EHCGFCEDSETRTGFCLPVDHNDVTLYSSTGLCTNGLDKSNSSFPNATSYVWQKHHCTTSYTILP 475

  Fly   338 LTLMGIVSFTASAGIVALTFVIIVELLPFKIRAPGISISMCGLSLSVF--IALITYPVL---IND 397
            :.:||:...|.|.|..:|.:|:..|..|...|:..:|||.  ||..||  |..:||..|   |..
 Worm   476 IVMMGVYLLTFSCGFTSLPWVLNSEFYPMWARSTCVSIST--LSNWVFNLIIALTYLSLTHAITK 538

  Fly   398 YGVHVTMFVSASFCLLGLVVLGIFLPETRGKSITQ 432
            ||   ..::.|.|.::..:.:...:|||.|.||.:
 Worm   539 YG---AFWLYAIFTIIAFIFIYFLVPETTGYSIDE 570

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14605	NP_649707.3	MFS	1..432	CDD:475125	120/553 (22%)
hmit-1.2	NP_507624.1	MFS	32..562	CDD:475125	114/545 (21%)