Protein Alignment CG14605 and hmit-1.1

DIOPT Version :10

• Sequence 1: NP_649707.3
• Gene: CG14605 / 40867
• FlyBaseID: FBgn0037486
• Length: 432
• Species: Drosophila melanogaster
• Sequence 2: NP_507623.1
• Gene: hmit-1.1 / 180205
• WormBaseID: WBGene00013073
• Length: 606
• Species: Caenorhabditis elegans
• Alignment Length: 514
• Identity: 111/514 - (21%)
• Similarity: 187/514 - (36%)
• Gaps: 169/514 - (32%)

  Fly    38 IGAS--FGIGCLICNMVICVPVSYFGIKKCMYFVPLPNILNWVLIYFASKSLYFYVCRVLLGISG 100
            :|||  |.||.|:|..         .:.|.|..|.                      ||||||:.
 Worm    99 LGASAIFTIGALVCAA---------SVNKIMLLVG----------------------RVLLGIAI 132

  Fly   101 GTLVVCFPVFIAEVSDNSVRGTLGSFFMMTLCSG-----IT-----------VGFVLVYCLSYHV 149
            |...:..||::.|.:...|||.|.:.|.:.:..|     ||           ||:.|::  ::..
 Worm   133 GFASMIVPVYLGETAPTHVRGMLVAAFALMISFGQVVANITGGAFSYIDPYNVGWRLMF--AFAA 195

  Fly   150 LPCVVIFLPILYLCLIIPLPEPPQDLLKRGHE-------EK---AEKSFCFYKNLSKDPAQQDDN 204
            :|.::.|:..::      |||.|:.|.:.|.|       ||   .:|.:..|: :::..|..:|.
 Worm   196 VPSIIQFVCFMF------LPETPRWLYENGFETETREVLEKVYNGDKEWVEYE-MAEIIAFNEDQ 253

  Fly   205 KAEFDKLRNKVLASG-IAEKI--TPADFFNKVSGKAFGLIAVLLLSNQMSGSFAIFNYSSTIFEQ 266
            ..|.:|..    ||| :..:|  ||...      ||..:.::|....|::|...|..|::.|...
 Worm   254 AKENEKAH----ASGPVIWRILKTPHVL------KACFIGSMLQAFQQLAGINTILYYTADIIRS 308

  Fly   267 LG-SRMEPNL-CGIFLGVVQIFGLISAVLLVDRVGRRLLLIPS--LAGMGLAELGVGLL------ 321
            .| |.....: ..:.|.:....|....:.|:::||||::.:.|  |..:.|..:||..|
 Worm   309 SGISNNHTTIWISVLLSLCNFIGPFVPMSLIEKVGRRIIFLFSCGLVVLSLVFIGVAFLLVNHDS 373

  Fly   322 ----------KSFASQ----------------------DFLH----------------------- 331
                      .:|.|.                      .|.|
 Worm   374 AATLPANQYGSNFNSSYPDAKGCMAYSNCDYCVTTDACGFCHDANTKQGYCLPAGFDNPEVYSST 438

  Fly   332 -----NNGWIA-------------LTLM-----GIVSFTASAGIVALTFVIIVELLPFKIRAPGI 373
                 :||.||             .||:     |:...|.|:|..:|.:|:..|..|...|:..:
 Worm   439 GSCTNSNGSIANNFKWEKYYCDTKYTLLPIIACGVYLLTFSSGFTSLPWVLNSEFYPMWARSTCV 503

  Fly   374 SISMCGLSLSVFIALITYPVLINDYGVHVTMFVSASFCLLGLVVLGIFLPETRGKSITQ 432
            :||.....:...|..:||..|....|.:...::.|...::..:.:...:|||:|.||.:
 Worm   504 AISTTSNWVFNLIIALTYLSLTQVIGKYGAFWLYAGLTVIAFIFILFLVPETKGYSIEE 562

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14605	NP_649707.3	MFS	1..432	CDD:475125	111/512 (22%)
hmit-1.1	NP_507623.1	MFS_HMIT_like	31..554	CDD:340918	105/504 (21%)