Protein Alignment CG14605 and hmit-1.3

DIOPT Version :10

• Sequence 1: NP_649707.3
• Gene: CG14605 / 40867
• FlyBaseID: FBgn0037486
• Length: 432
• Species: Drosophila melanogaster
• Sequence 2: NP_497725.2
• Gene: hmit-1.3 / 175458
• WormBaseID: WBGene00010811
• Length: 604
• Species: Caenorhabditis elegans
• Alignment Length: 515
• Identity: 108/515 - (20%)
• Similarity: 188/515 - (36%)
• Gaps: 170/515 - (33%)

  Fly    38 IGAS--FGIGCLICNMVICVPVSYFGIKKCMYFVPLPNILNWVLIYFASKSLYFYVCRVLLGISG 100
            ||||  |.||.:||...                        |.       .:...:.|:|||::.
 Worm   102 IGASVTFTIGAIICAAA------------------------WT-------KIILLIGRILLGLAI 135

  Fly   101 GTLVVCFPVFIAEVSDNSVRGTLGSFFMMTLCSGITVGFVLVYCLSY--------------HVLP 151
            |...:..|::::|.|.:.:||.|.:.|.:.:..|:.:..::....||              ..:|
 Worm   136 GFASMIVPIYVSEASPSHIRGKLVTGFQLMITVGLVIANIIGGAFSYVDPDQVGWRLMFAFAAVP 200

  Fly   152 CVVIFLPILYLCLIIPLPEPPQDLLKRGHEEKAEKSFCFYKNLSKDPAQQDDNKAEF---DKLRN 213
            .::.|:..|:      |||.|:.|.:.|...:|.:......|...:....:.|:..|   ::||.
 Worm   201 AIIQFVCFLF------LPESPRWLYEHGRTVEAREVLTRIYNGHTEWVDYEINEISFSYEEELRA 259

  Fly   214 KVLASGIAEKI-----TPADFFNKVSGKAFGLIAVLLLSNQMSGSFAIFNYSSTIFEQLGSRMEP 273
            |...:|....|     ||.      ..||..:.::|.:..|:||...:..|:..|....|  ::.
 Worm   260 KAEHAGNGPTIIRILKTPH------VRKAMIIGSLLQMFQQLSGINTVMYYTGNIIRSAG--VKD 316

  Fly   274 NLCGIFLGV----VQIFGLISAVLLVDRVGRRLLLIPSLAGMGLAELGVGL---------LKSFA 325
            |...|::.|    :...|....:.||:|||||:||:.|:.|:.|..:.:|:         |::|.
 Worm   317 NHTTIWISVGTSAINFLGTFIPIALVERVGRRVLLLVSMIGVILFLIAMGVSFLLINNDSLRTFD 381

  Fly   326 SQDF------------------------------------------------------------- 329
            .|::
 Worm   382 QQNYTLNYNPSVKHAAKCLKYSNCDFCVTDENCGFCESKVAKKGYCLPFPSDDSSDYSATGICEF 446

  Fly   330 --LHNNG----W-------------IALTLMGIVSFTASAGIVALTFVIIVELLPFKIRAPGISI 375
              |.|||    |             |.:.:..::||  |||...|.:|:..|..|...|:..:|:
 Worm   447 SNLTNNGTDFEWEDTYCHTKFTVLPIIIMVFYLLSF--SAGYAPLPWVLNAEFYPLWARSTAVSV 509

  Fly   376 S-MCG--LSLSVFIALITYPVLINDYGVHVTMFVSASFCLLGLVVLGIFLPETRGKSITQ 432
            | .|.  .:|.|.:..::.......||   |.|:.....::.||.:..|:|||:|.||.:
 Worm   510 STACNWIFNLIVSLTFLSLSQAATKYG---TFFIYCGCTMVALVFVFFFVPETKGYSIDE 566

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14605	NP_649707.3	MFS	1..432	CDD:475125	108/513 (21%)
hmit-1.3	NP_497725.2	MFS	34..558	CDD:475125	102/505 (20%)
		MFS	<190..>249	CDD:475125	12/64 (19%)