DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14606 and HXT5

DIOPT Version :9

Sequence 1:	NP_001334690.1	Gene:	CG14606 / 40866	FlyBaseID:	FBgn0037485	Length:	466	Species:	Drosophila melanogaster
Sequence 2:	NP_011964.1	Gene:	HXT5 / 856496	SGDID:	S000001138	Length:	592	Species:	Saccharomyces cerevisiae

Alignment Length:	500	Identity:	107/500 - (21%)
Similarity:	198/500 - (39%)	Gaps:	117/500 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 IMTLTHGIAVGW----------LSPSLRLLASDESPLGDPLTITQASWVGSLIGLGSLTGNIIFG 82
            :|....|...||          .:..:|...|..:.....|:..:...:.|:..:|...|.|:..
Yeast    91 LMVAFGGFVFGWDTGTISGFVRQTDFIRRFGSTRANGTTYLSDVRTGLMVSIFNIGCAIGGIVLS 155

  Fly    83 LLLDRLGRKVCMYFLAIPNMIYWILIYSAQDVTYLY-AGRFLAGMSGGGCYVVLPIFIAEIADNS 146
            .|.|..|||:.:..:.:...|..|:..::.|..|.| .||.::|:..||..|:.|:.|:|::...
Yeast   156 KLGDMYGRKIGLMTVVVIYSIGIIIQIASIDKWYQYFIGRIISGLGVGGITVLAPMLISEVSPKQ 220

  Fly   147 VRGALSSMAMMYVSIGMMVGFTL------ASYLPYYLMPCIIVALPVVFMLSVIGLS---ETPQY 202
            :||.|.|...:.::.|:.:|:..      .|....:.:|..:.....:||  ::|::   |:|:|
Yeast   221 LRGTLVSCYQLMITFGIFLGYCTNFGTKNYSNSVQWRVPLGLCFAWSIFM--IVGMTFVPESPRY 283

  Fly   203 LLRRGRDDQAEKSFYFYKNLTPPTSSDKEASQHDAAKIEFDTFRLQVLSGGVTESISWRDFI-NV 266
            |:..|:.::|::|.         ..::|.........:|.:.::..:.:..:..|.||.:.: ..
Yeast   284 LVEVGKIEEAKRSL---------ARANKTTEDSPLVTLEMENYQSSIEAERLAGSASWGELVTGK 339

  Fly   267 PTL---KIFGLIFVLIICNQLSGSFAIFNYTSHIFAELGNNLDPNTSTIVVGAAQLVGIFSAVVL 328
            |.:   .:.|::...:  .||:|....|.|.:.||..:|.. |...:.||:|....|..|.::..
Yeast   340 PQMFRRTLMGMMIQSL--QQLTGDNYFFYYGTTIFQAVGLE-DSFETAIVLGVVNFVSTFFSLYT 401

  Fly   329 VDRLGRRVLLLTSMGGM--------------------------GLGELAIAL----LKCFASDEF 363
            |||.|||..||....||                          |.|...|..    :.|||:.
Yeast   402 VDRFGRRNCLLWGCVGMICCYVVYASVGVTRLWPNGQDQPSSKGAGNCMIVFACFYIFCFATT-- 464

  Fly   364 LNQNGWLPLVIMCLVACIASLGVIALIFIIIIELLPAKIRSIGTSLSMAT------------FSG 416
                 |.|:.                 :::|.|..|.::|  |.::|:|:            |:.
Yeast   465 -----WAPVA-----------------YVLISESYPLRVR--GKAMSIASACNWIWGFLISFFTP 505

  Fly   417 FIFVALKIYPTMIYDQGLAATMFMSAGMCLFGFIVLGLFLPETKG 461
            ||..|:..|...::           .|..:|.:..:..|:|||||
Yeast   506 FITSAINFYYGYVF-----------MGCMVFAYFYVFFFVPETKG 539

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14606	NP_001334690.1	None
HXT5	NP_011964.1	Sugar_tr	89..549	CDD:395036	106/499 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157342534
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
TreeFam	0	0.000	Not matched by this tool.
	4	3.740