DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14606 and HXT1

DIOPT Version :9

Sequence 1:	NP_001334690.1	Gene:	CG14606 / 40866	FlyBaseID:	FBgn0037485	Length:	466	Species:	Drosophila melanogaster
Sequence 2:	NP_011962.1	Gene:	HXT1 / 856494	SGDID:	S000001136	Length:	570	Species:	Saccharomyces cerevisiae

Alignment Length:	501	Identity:	112/501 - (22%)
Similarity:	192/501 - (38%)	Gaps:	119/501 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 IMTLTHGIAVGW----------LSPSLRLLASDESPLGDPLTITQASWVGSLIGLGSLTGNIIFG 82
            :|....|...||          .:..||............|:..:...:.|:..:|...|.|:..
Yeast    70 VMVAFGGFIFGWDTGTISGFVAQTDFLRRFGMKHHDGSHYLSKVRTGLIVSIFNIGCAIGGIVLA 134

  Fly    83 LLLDRLGRKVCMYFLAIPNMIYWILIYSAQDVTYLY-AGRFLAGMSGGGCYVVLPIFIAEIADNS 146
            .|.|..||::.:..:.:...|..|:..::.:..|.| .||.::|:..||..|:.|:.|:|:|.:.
Yeast   135 KLGDMYGRRIGLIVVVVIYTIGIIIQIASINKWYQYFIGRIISGLGVGGITVLSPMLISEVAPSE 199

  Fly   147 VRGALSSMAMMYVSIGMMVG----FTLASY-------LPYYLMPCIIVALPVVFML-SVIGLSET 199
            :||.|.|...:.:::|:.:|    |...:|       :|..|  |...||   ||: .::.:.|:
Yeast   200 MRGTLVSCYQVMITLGIFLGYCTNFGTKNYSNSVQWRVPLGL--CFAWAL---FMIGGMMFVPES 259

  Fly   200 PQYLLRRGRDDQAEKSFYFYKNLTPPTSSDKEASQHDAAKIEFDTFRLQVLSGGVTESISWRD-F 263
            |:||:..||.|:|..|. ...|..||        .|...:.|.:|....|.......:.||.: |
Yeast   260 PRYLVEAGRIDEARASL-AKVNKCPP--------DHPYIQYELETIEASVEEMRAAGTASWGELF 315

  Fly   264 INVPTL---KIFGLIFVLIICNQLSGSFAIFNYTSHIFAELGNNLDPNTSTIVVGAAQLVGIFSA 325
            ...|.:   .:.|::...:  .||:|....|.|.:.:|..:|.: |...::||.|.........:
Yeast   316 TGKPAMFQRTMMGIMIQSL--QQLTGDNYFFYYGTIVFQAVGLS-DSFETSIVFGVVNFFSTCCS 377

  Fly   326 VVLVDRLGRRVLLLTSMGGM--------------------------GLGELAIAL----LKCFAS 360
            :..|||.|||..|:....||                          |.|...|..    :.|||:
Yeast   378 LYTVDRFGRRNCLMWGAVGMVCCYVVYASVGVTRLWPNGQDQPSSKGAGNCMIVFACFYIFCFAT 442

  Fly   361 DEFLNQNGWLPLVIMCLVACIASLGVIALIFIIIIELLPAKIRSIGTSLSMAT----------FS 415
            .       |.|:.                 :::|.|..|.:::|...|::.|.          |:
Yeast   443 T-------WAPIA-----------------YVVISECFPLRVKSKCMSIASAANWIWGFLISFFT 483

  Fly   416 GFIFVALKIYPTMIYDQGLAATMFMSAGMCLFGFIVLGLFLPETKG 461
            .||..|:..|...::           .|..:|.:..:..|:|||||
Yeast   484 PFITGAINFYYGYVF-----------MGCMVFAYFYVFFFVPETKG 518

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14606	NP_001334690.1	None
HXT1	NP_011962.1	Sugar_tr	68..528	CDD:395036	112/501 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157342527
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
TreeFam	0	0.000	Not matched by this tool.
	4	3.740