DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG14606 and MPH2

DIOPT Version :9

Sequence 1:	NP_001334690.1	Gene:	CG14606 / 40866	FlyBaseID:	FBgn0037485	Length:	466	Species:	Drosophila melanogaster
Sequence 2:	NP_010034.1	Gene:	MPH2 / 851350	SGDID:	S000002406	Length:	609	Species:	Saccharomyces cerevisiae

Alignment Length:	496	Identity:	103/496 - (20%)
Similarity:	197/496 - (39%)	Gaps:	102/496 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 THGIAVGW---LSPSLRLLASDESPLGD--PLTITQ----------------ASW---------V 66
            |:..|..|   :|.:|.:...|.:.||.  .|.|.|                |||         .
Yeast    93 TYPKAAAWSLLVSTTLIMEGYDTAILGAFYALPIFQRKFGSQNDKTGEWEISASWQIGLTLCYMA 157

  Fly    67 GSLIGLGSLTGNIIFGLLLDRLGRK----VCMYFLAIPNMIYWILIYSAQDVTYLYAGRFLAGMS 127
            |.::|| .|||..:     |.:|.:    :.::|||    .:..::|....:..:..|:.|.||.
Yeast   158 GEIVGL-QLTGPSV-----DLVGNRYTLIIALFFLA----AFTFILYFCNSLGMIAVGQALCGMP 212

  Fly   128 GGGCYVVLPI-FIAEIADNSVRGALSSMAMMYVSIGMM--VGFTLASYLPY------YLMPCIIV 183
             .||:..|.: :.:||...::|..|::.:.:....|.:  .|....|...|      |.:|..:.
Yeast   213 -WGCFQCLTVSYASEICPLALRYYLTTYSNLCWLFGQLFAAGIMKNSQKKYADSELGYKLPFALQ 276

  Fly   184 -ALPVVFMLSVIGLSETPQYLLRRGRDDQAEKSFYFYKNLTPPTSSDKEASQHDAAKIEFDTFRL 247
             .|||...|.:....|:|.:|:::||.|:|.:|.       ..|.|.|...:.....:|.|..::
Yeast   277 WILPVPLALGIFFAPESPWWLVKKGRFDEARRSL-------RRTLSGKGPEKEILVTLEVDKIKV 334

  Fly   248 ------QVLSGGVTESISWRDFINVPTLKIFGLIFVLIICNQLSGSFAIFNYTSHIFAELGNNLD 306
                  ::.|...:.|..:.|.||....:|..|.:    ..|.:....:..|:::.:.:.|.:.:
Yeast   335 TIDKEKRLTSKEGSYSDCFEDKINRRRTRITCLCW----AGQATCGSILIGYSTYFYEKAGVSTE 395

  Fly   307 PN-TSTIVVGAAQLVGIFSAVVLVDRLGR----------RVLLLTSMGGMGLGELAIALLKCFAS 360
            .: |.:|:.....:...|.:.......||          :.::...:||:|          |.::
Yeast   396 MSFTFSIIQYCLGICATFLSWWASKYFGRYDLYAFGLAFQTIVFFIIGGLG----------CSST 450

  Fly   361 DEFLNQNGWLPLVIMCLVACIASLGVIALIFIIIIELLPAKIRSIGTSLSMATFS--GFIFVALK 423
            ......:|.|    :..||...:||:..::|.::.|:..:::|:....|:..|::  ..|...|.
Yeast   451 HGSKMGSGSL----LMAVAFFYNLGIAPVVFCLVSEMPSSRLRTKTIILARNTYNVVSIICSVLI 511

  Fly   424 IYP--TMIYDQGLAATMFMSAGMCLFGFIVLGLFLPETKGK 462
            :|.  :..::.|..:..|... :|....|...:.||||.||
Yeast   512 LYQLNSKKWNWGAKSGFFWGV-LCFCTLIWAVVDLPETAGK 551

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14606	NP_001334690.1	None
MPH2	NP_010034.1	SP	72..556	CDD:273317	103/496 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157342474
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.830