DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14606 and HXT10

DIOPT Version :9

Sequence 1:	NP_001334690.1	Gene:	CG14606 / 40866	FlyBaseID:	FBgn0037485	Length:	466	Species:	Drosophila melanogaster
Sequence 2:	NP_116644.1	Gene:	HXT10 / 850536	SGDID:	S000001883	Length:	546	Species:	Saccharomyces cerevisiae

Alignment Length:	513	Identity:	110/513 - (21%)
Similarity:	209/513 - (40%)	Gaps:	95/513 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 PSQKLSVFSVRYRWQFIATMTVH---IMTLTHGIAVGWLSPSL--------------RLLASDES 52
            |..:.:...:.|: ..||..||.   :|....|...||.:.::              .|......
Yeast    29 PETREASLDIPYK-PIIAYWTVMGLCLMIAFGGFIFGWDTGTISGFINQTDFKRRFGELQRDGSF 92

  Fly    53 PLGDPLTITQASWVGSLIG---LGSLTGNIIFGLLLDRLGRKVCMYFLAIPNMIYWILIYSAQDV 114
            .|.|..|       |.::|   :|...|.:..|.|.|..|||:.:..:.:..::..::..::.|.
Yeast    93 QLSDVRT-------GLIVGIFNIGCALGGLTLGRLGDIYGRKIGLMCVILVYVVGIVIQIASSDK 150

  Fly   115 TYLY-AGRFLAGMSGGGCYVVLPIFIAEIADNSVRGALSSMAMMYVSIGMMVGF-------TLAS 171
            .|.| .||.::||..||..|:.|..|:||:...:||...|...:.:::|:.:|:       ..::
Yeast   151 WYQYFIGRIVSGMGVGGVAVLSPTLISEISPKHLRGTCVSFYQLMITLGIFLGYCTNYGTKKYSN 215

  Fly   172 YLPYYLMPCIIVALPVVFMLSVIGLSETPQYLLRRGRDDQAEKSFYFYKNLTPPTSSDKEASQHD 236
            .:.:.:...:..|..:..::.::.:.|:|:||:.:|:.::|.:|.         ..|:|......
Yeast   216 SIQWRVPLGLCFAWAIFMVIGMVMVPESPRYLVEKGKYEEARRSL---------AKSNKVTVTDP 271

  Fly   237 AAKIEFDTFRLQVLSGGVTESISWRDFIN-----VPTLKIFGLIFVLIICNQLSGSFAIFNYTSH 296
            ....||||....:.......:.||.:..:     :|.: |.|::...:  .||:|....|.|.:.
Yeast   272 GVVFEFDTIVANMELERAVGNASWHELFSNKGAILPRV-IMGIVIQSL--QQLTGCNYFFYYGTT 333

  Fly   297 IFAELGNNLDPNTSTIVVGAAQLVGIFSAVVLVDRLGRRVLLLTSMGGMGLGELAIALLKCF--- 358
            ||..:|.. |...::||:||......|.|:.:||:.|||..||.....|.:         ||
Yeast   334 IFNAVGMQ-DSFETSIVLGAVNFASTFVALYIVDKFGRRKCLLWGSASMAI---------CFVIF 388

  Fly   359 -----------ASDEFLNQN-GWLPLVIMCLVACIASLGVIALIFIIIIELLPAKIR------SI 405
                       ..|:..:|: |.:.:|..|......::....:.::|:.|..|.:::      ::
Yeast   389 ATVGVTRLWPQGKDQPSSQSAGNVMIVFTCFFIFSFAITWAPIAYVIVAETYPLRVKNRAMAIAV 453

  Fly   406 GTSLSMATFSGFI--FVALKIYPTMIYDQGLAATMFMSAGMCLFGFIVLGLFLPETKG 461
            |.:.......||.  |:...|..:..|       :||  |..:|.:..:..|:.||||
Yeast   454 GANWMWGFLIGFFTPFITRSIGFSYGY-------VFM--GCLIFSYFYVFFFVCETKG 502

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14606	NP_001334690.1	None
HXT10	NP_116644.1	Sugar_tr	52..512	CDD:395036	104/489 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157342540
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
TreeFam	0	0.000	Not matched by this tool.
	3	2.830