Protein Alignment CG14606 and SLC2A2

DIOPT Version :9

• Sequence 1: NP_001334690.1
• Gene: CG14606 / 40866
• FlyBaseID: FBgn0037485
• Length: 466
• Species: Drosophila melanogaster
• Sequence 2: NP_000331.1
• Gene: SLC2A2 / 6514
• HGNCID: 11006
• Length: 524
• Species: Homo sapiens
• Alignment Length: 484
• Identity: 118/484 - (24%)
• Similarity: 204/484 - (42%)
• Gaps: 93/484 - (19%)

  Fly    20 FIATMTVHIMTLTHGIAVGWLSPSLRLLASDESPLGDPLTITQASWVGSLIGLGSLTGNIIFGLL 84
            ::...|..:.|:::.     ::|.....|.:|:.....|.....|...|...:|.:|.:...|.|
Human    59 YVINSTDELPTISYS-----MNPKPTPWAEEETVAAAQLITMLWSLSVSSFAVGGMTASFFGGWL 118

  Fly    85 LDRLGRKVCMYFLAIPNMIYWILI-YSAQDVTY--LYAGRFLAGMSGGGCYVVLPIFIAEIADNS 146
            .|.|||...|....|.:::..:|: :|....::  :.|||.::|:..|....::|::|.|||..:
Human   119 GDTLGRIKAMLVANILSLVGALLMGFSKLGPSHILIIAGRSISGLYCGLISGLVPMYIGEIAPTA 183

  Fly   147 VRGALSSMAMMYVSIGMMVG------FTLASYLPYYLMPCIIVALPVVFMLSVIGLSETPQYLL- 204
            :||||.:...:.:..|:::.      |.|.:|..::::..:.....::..|.:....|:|:||.
Human   184 LRGALGTFHQLAIVTGILISQIIGLEFILGNYDLWHILLGLSGVRAILQSLLLFFCPESPRYLYI 248

  Fly   205 --------------RRGRDDQAEKSFYFYKNLTPPTSSDKEASQHDAAKIEFDTFRLQVLSGGVT 255
                          .||.||..       |::.......:|||......|      :|:.:..
Human   249 KLDEEVKAKQSLKRLRGYDDVT-------KDINEMRKEREEASSEQKVSI------IQLFTNS-- 298

  Fly   256 ESISWRDFINVPTLKIFGLIFVLIICNQLSGSFAIFNYTSHIFAELGNNLDPNTSTIVVGAAQLV 320
               |:|.    |.|    :..:|.:..|.||...||.|::.||...|.: .|..:||.|||..:|
Human   299 ---SYRQ----PIL----VALMLHVAQQFSGINGIFYYSTSIFQTAGIS-KPVYATIGVGAVNMV 351

  Fly   321 GIFSAVVLVDRLGRRVLLLTSMGGMGLGE--LAIALLKCFASDEFLNQNGWLPLVIMCLVACIAS 383
            ....:|.||::.|||.|.|..|.||.:..  :::.|:       .||:..|:..|.|
Human   352 FTAVSVFLVEKAGRRSLFLIGMSGMFVCAIFMSVGLV-------LLNKFSWMSYVSM-------- 401

  Fly   384 LGVIALIFIIIIELLP--------AKIRSIG---TSLSMATFSGF---IFVALKIYPTMIYDQGL 434
              :...:|:...|:.|        |:..|.|   .:|::|.||.:   ..|||..  ..|.|...
Human   402 --IAIFLFVSFFEIGPGPIPWFMVAEFFSQGPRPAALAIAAFSNWTCNFIVALCF--QYIADFCG 462

  Fly   435 AATMFMSAGMCLFGFIVLGLF-LPETKGK 462
            ....|:.||: |..|.:...| :||||||
Human   463 PYVFFLFAGV-LLAFTLFTFFKVPETKGK 490

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14606	NP_001334690.1	None
SLC2A2	NP_000331.1	Sugar_tr	14..499	CDD:278511	118/484 (24%)
		MFS	98..485	CDD:119392	106/433 (24%)
		Monosaccharide binding. /evidence=ECO:0000250|UniProtKB:P11166	314..320		3/5 (60%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165144109
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D430696at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.850