DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14606 and slc2a6

DIOPT Version :9

Sequence 1:	NP_001334690.1	Gene:	CG14606 / 40866	FlyBaseID:	FBgn0037485	Length:	466	Species:	Drosophila melanogaster
Sequence 2:	XP_689092.6	Gene:	slc2a6 / 560602	ZFINID:	ZDB-GENE-081104-301	Length:	490	Species:	Danio rerio

Alignment Length:	472	Identity:	116/472 - (24%)
Similarity:	212/472 - (44%)	Gaps:	51/472 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 FIATMTVHIMTLTHGIAVGWLSPSL-RLLASDESPLGDPLTITQASWVGSLIGLGSLTGNIIFGL 83
            ::|..:..:.....|.|:.:.||.: :|...|::.|  .:.:.|.||.||:..||:..|.:....
Zfish    25 YLAVFSAVLGNFNFGFALVFPSPVIPQLKQGDDTRL--QMNVHQISWFGSIFTLGAAAGGLSAMF 87

  Fly    84 LLDRLGRKVCMYFLAIPNMIYWILIYSAQDVTYLYAGRFLAGMSGGGCYVVLPIFIAEIADNSVR 148
            |.||:|||:.:....:|:::..:::.|||:...|..||||.|::||.....:|::::||:..|||
Zfish    88 LNDRVGRKISIMISGLPSVLGLLVMGSAQNFWMLLWGRFLTGIAGGITAGSIPVYVSEISHPSVR 152

  Fly   149 GALSSMAMMYVSIGMMVGFTLASYLPYYLMPCIIVALPVVFMLSVIGLSET-PQYLLRRGRDDQA 212
            |||.|...:....|.:..:.....||:..: .:...:|||.|:.::....| |:|.:.:|...:|
Zfish   153 GALGSCPQITAVFGSLALYAFGLILPWRWL-AVAGEVPVVIMMLLLCCMPTSPRYHIMKGNRAKA 216

  Fly   213 EKSFYFYKNLTPPTSSDKEASQHDAAKIEFDTFRLQVLSGGVTESISWRDFINVPTLKIFGLIFV 277
            .||..:   |..|.|.         ...||:.....:    .|:.:.|.|.......|...:..|
Zfish   217 VKSLEW---LRGPNSD---------YMTEFNKIERSI----TTQGVQWSDLKTKSYYKPILISVV 265

  Fly   278 LIICNQLSGSFAIFNYTSHIFAELGNNLDPNTSTIVVGAAQLVGIFSAVVLVDRLGRRVLLLTSM 342
            :....|::|...|..|...||.....:|:|.....:|||.:|:.:..|..|:|:.||:.||.||
Zfish   266 MRFLQQMTGITPILVYLEPIFHLTAISLEPKYDAALVGAVRLISVAIAASLMDKAGRKALLFTS- 329

  Fly   343 GGMGLGELAIALLK---------CFASD----EFLN-----QNG-------WLPLVIMCLVACIA 382
            |.:    :.||:|.         |...:    :.||     |.|       .:||:...::....
Zfish   330 GFL----IYIAMLSMTMYTHQTPCSQGNLTLTDGLNISSEVQAGAAFDPKTLIPLISAMVIIFGY 390

  Fly   383 SLGVIALIFIIIIELLPAKIRSIGTSLSMATFSGFIFVALKIYPTMIYDQGLAATMFMSAGMCLF 447
            ::|...:.::::.|:||...|.:.:.|.:.......||..:::..::...||.........:.:.
Zfish   391 AMGWGPITWLLMSEILPLGARGVASGLCVGVSWITAFVLTQLFMHVVVAYGLYVPFLFFCVVSVV 455

  Fly   448 GFIVLGLFLPETKGKLM 464
            ..|.....:|||||:.:
Zfish   456 NIIFTAKCVPETKGRTL 472

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14606	NP_001334690.1	None
slc2a6	XP_689092.6	Sugar_tr	27..479	CDD:278511	116/470 (25%)
slc2a6	XP_689092.6	MFS	28..461	CDD:119392	110/456 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170577119
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53651
OrthoDB	1	1.010	-	-		D430696at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48021
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.860