DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG14606 and slc2a3a

DIOPT Version :9

Sequence 1:	NP_001334690.1	Gene:	CG14606 / 40866	FlyBaseID:	FBgn0037485	Length:	466	Species:	Drosophila melanogaster
Sequence 2:	XP_005159482.1	Gene:	slc2a3a / 436916	ZFINID:	ZDB-GENE-040718-390	Length:	575	Species:	Danio rerio

Alignment Length:	512	Identity:	121/512 - (23%)
Similarity:	217/512 - (42%)	Gaps:	110/512 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 PSQKLSVFSVRYRWQFIATMTVHIMTLTHGIAVGWLSPSLRLLASDESPLGDPL-----TITQAS 64
            |.|||..|       |.||               |:           ...|:|:     ||.. |
Zfish    36 PEQKLRAF-------FNAT---------------WM-----------ERYGEPISPGVCTIVW-S 66

  Fly    65 WVGSLIGLGSLTGNIIFGLLLDRLGRKVCMYFLAIPNMIYWI------LIYSAQDVTYLYAGRFL 123
            :..::..:|.:.|:...|::.::.||:..|..:   |::..|      |.........:.|||.:
Zfish    67 FAVAIFSVGGMAGSFSVGVVANKFGRRKSMILV---NVLALIGGGLMGLCTLCSSFEMIIAGRLM 128

  Fly   124 AGMSGGGCYVVLPIFIAEIADNSVRGALSSMAMMYVSIGMMVG--FTLASYL------PYYLMPC 180
            .|:..|....:.|:::.|::...:|||..::..:.|.:|:::.  |.|.|.|      |..|...
Zfish   129 IGLFCGLFTGLTPMYVGEVSPTPLRGAFGTLHQLGVVVGILIAQIFGLESLLGSDKLWPILLALT 193

  Fly   181 IIVALPVVFMLSVIGLSETPQYLL-RRGRDDQAEKSFYFYKNLTPPTSSDKEASQHDAAKIEFDT 244
            |:.|:...|:|..  ..|:|:||| ....::||.|:....:.. .....|.:..:.::||:..:.
Zfish   194 ILPAILQCFLLPF--CPESPRYLLINLNEEEQARKALVRLRGY-EDVGKDMQEMKEESAKMAMEK 255

  Fly   245 FRLQVLSGGVTESISWRD--FINVPTLKIFGLIFVLIICNQLSGSFAIFNYTSHIFAELGNNLDP 307
               :|....:..|.::|.  ||.:          :|.:..||||..|:|.|::.||...|.. .|
Zfish   256 ---KVTIPELFRSAAYRQPLFIAI----------MLQLSQQLSGINAVFYYSTGIFKSAGVT-QP 306

  Fly   308 NTSTIVVGAAQLVGIFSAVVLVDRLGRRVLLLTSMGGMGLGELA--IALL-----KCFASDEFLN 365
            ..:||..|....|....::.||:|.|||.|.|..:|||.:..||  ||||     .||...:.||
Zfish   307 IYATIGAGVVNTVFTVVSLFLVERAGRRTLHLIGLGGMAISALAMTIALLLVRFTVCFNFVKILN 371

  Fly   366 Q-NGWLPLVIMCLVACIAS---------LGVIALI-FIIIIELLP--------AKIRSIG---TS 408
            | ..:|.:::...:..::.         |.:.|:. |:.:.|:.|        |::.|.|   .:
Zfish   372 QPQQYLMIMVNVFITFVSKQKDIEALQYLSIAAIFAFVAMFEMGPGPIPWFIVAELFSQGPRPAA 436

  Fly   409 LSMATFSGFI--FVALKIYPTMIYDQGLAATMFMSAGMCLFGFIVLGLF-LPETKGK 462
            :::|..|.:.  |:....:|.:  ::.....:|:...:.|..|.:...| :|||||:
Zfish   437 MAVAGCSNWTANFIVGITFPKL--EELCGPYVFIIFMIFLIIFFIFTYFKVPETKGR 491

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14606	NP_001334690.1	None
slc2a3a	XP_005159482.1	Sugar_tr	18..500	CDD:278511	121/512 (24%)
slc2a3a	XP_005159482.1	MFS	66..466	CDD:119392	99/421 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170576897
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.840