DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG14606 and CG1213

DIOPT Version :9

Sequence 1:	NP_001334690.1	Gene:	CG14606 / 40866	FlyBaseID:	FBgn0037485	Length:	466	Species:	Drosophila melanogaster
Sequence 2:	NP_001246937.1	Gene:	CG1213 / 40728	FlyBaseID:	FBgn0037387	Length:	491	Species:	Drosophila melanogaster

Alignment Length:	456	Identity:	125/456 - (27%)
Similarity:	219/456 - (48%)	Gaps:	36/456 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 FIATMTVHIMTLTHGIAVGWLS---PSLRLLASDESPLGDPLTITQASWVGSLIGLGSLTGNIIF 81
            |:|.:..::.....|..:||.|   |.|:...:.:|||..|:|..:.:|:.|||.:|:|....:.
  Fly    43 FMAAVAANLSAFVVGTTLGWTSPIGPKLKSEDTSDSPLSRPITSDEDAWISSLIAVGALVAPFVA 107

  Fly    82 GLLLDRLGRKVCMYFLAIPNMIYWILIYS----AQDVTYLYAGRFLAGMSGGGCYVVLPIFIAEI 142
            |.:.||:|||    ::.:.:.::::|.:.    |.:|..||..|.:.|...|....|.|:::.||
  Fly   108 GPMADRIGRK----WVLLSSSLFFVLAFGLNMVASEVWILYMSRLIQGFGVGFVMTVQPMYVGEI 168

  Fly   143 ADNSVRGALSSMAMMYVSIGMMVGFTLASYLPYYLMPCIIVALPVVFMLSVIGLSETPQYLLRRG 207
            :.::||||..|:..:::..|::..:.:..|:.|..:....:.:||||.|....:.|:|.:...:|
  Fly   169 STDNVRGATGSLMQLFIVGGILYVYAIGPYVSYQALQWCCIVVPVVFDLVFYMMPESPYFFAGKG 233

  Fly   208 RDDQAEKSFYFYKNLTPPTSSDKEASQHDAAKIEFDTFRLQVLSGGVTESISWRDFINVPTLKIF 272
            |..:|.||..|.:      ....|....:.|:|:.:........|.|.:.     |.|....:..
  Fly   234 RKSEALKSLQFLR------GQSAEGVHDEMAEIQANVEEAMASKGTVMDL-----FKNAGNRRAL 287

  Fly   273 GLIFVLIICNQLSG-SFAIFNYTSHIFAELGNNLDPNTSTIVVGAAQLVGIFSAVVLVDRLGRRV 336
            .:...||...|||| :..:||..| |||.....|||..:||::|..|:.......::.|||||:|
  Fly   288 FICAGLISFQQLSGINVVLFNSQS-IFASANTGLDPAIATIIIGCVQVGSSALTPLVADRLGRKV 351

  Fly   337 LLLTSMGGMGLGELAIA---LLKCFASDEFLNQNGWLP---LVIMCLVACIASLGVIALIFIIII 395
            :||||...|.:|..|:.   .::....|  ::...|:|   |:|..:|.|   .|...|.:.::.
  Fly   352 MLLTSSSVMSIGLAALGAFFYMQLVKGD--ISSVVWMPVPALIIYNIVYC---TGFGPLPWAVLG 411

  Fly   396 ELLPAKIRSIGTSLSMATFSGFIFVALKIYPTMIYDQGLAATMFMSAGMCLFGFIVLGLFLPETK 460
            |:.||.|:|:.:|:..:|.....|:....||::.......|....:..|.:..|.||.:.: |||
  Fly   412 EMFPANIKSVASSVVASTCWTLGFLVTFFYPSLDALGSYYAFWLFAVCMVVAFFFVLFVVM-ETK 475

  Fly   461 G 461
            |
  Fly   476 G 476

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14606	NP_001334690.1	None
CG1213	NP_001246937.1	SP	42..482	CDD:273317	125/456 (27%)
CG1213	NP_001246937.1	MFS	47..460	CDD:119392	115/433 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D430696at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR48021
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
	5	4.920