DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG14606 and CG10960

DIOPT Version :9

Sequence 1:	NP_001334690.1	Gene:	CG14606 / 40866	FlyBaseID:	FBgn0037485	Length:	466	Species:	Drosophila melanogaster
Sequence 2:	NP_648605.1	Gene:	CG10960 / 39458	FlyBaseID:	FBgn0036316	Length:	539	Species:	Drosophila melanogaster

Alignment Length:	463	Identity:	129/463 - (27%)
Similarity:	216/463 - (46%)	Gaps:	43/463 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 RW-QFIATMTVHIMTLTHGIAVGWLSPSLRLLASDESPLGDPLTITQASWVGSLIGLGSLTGNII 80
            :| |::|.:.........|..:||.||:...:.........|:...|.|||||.:.||:....|.
  Fly    80 KWPQYVAALAAAGGAFAAGTVLGWTSPAETEIVDRGEGYDFPVDKDQFSWVGSAMTLGAACVCIP 144

  Fly    81 FGLLLDRLGRKVCMYFLAIPNMIYWILIYSAQDVTYLYAGRFLAGMSGGGCYVVLPIFIAEIADN 145
            .|.|::.:|||..|.||.:|.::.|.::..|.:|:.|||.||:.|::||...|..|::..|||..
  Fly   145 IGFLINMIGRKWTMLFLVLPFILGWTMLIWAVNVSMLYASRFILGIAGGAFCVTAPMYTGEIAQK 209

  Fly   146 SVRGALSSMAMMYVSIGMMVGFTLASYLPYYLMPCIIVALPVVFMLSVIGLSETPQYLLRRGRDD 210
            .:||.|.|...:.::||::..:.:.:.:..:.:..|...||::|......:.|:|.||:.:.|.:
  Fly   210 EIRGTLGSFFQLMITIGILFVYAVGAGVKIFWLSIICGILPLIFGAIFFFMPESPTYLVSKDRSE 274

  Fly   211 QAEKSF-------YFYK-NLTPPTSSDKEASQHDAAKIEFDTFRLQVLSGGVTESISWRDFINVP 267
            .|.||.       |.|: .|.....:|:|..   |.|:..                 |.......
  Fly   275 NAIKSIQWLRGKEYDYEPELAELRETDRETK---ANKVNV-----------------WAALNRPV 319

  Fly   268 TLKIFGLIFVLIICNQLSGSFAIFNYTSHIFAELGNNLDPNTSTIVVGAAQLVGIFSAVVLVDRL 332
            |.|...:...|:...|:.|..|:..|.|.||.|....::...:||::|..|:|..|.:.::||:|
  Fly   320 TRKALAISMGLMFFQQVCGINAVIFYASRIFLEANTGIEAEWATILIGIMQVVATFVSTLVVDKL 384

  Fly   333 GRRVLLLTSMGGMGLGELAIALLKCFASDEFLNQN--------GWLPLVIMCLVACIASLGVIAL 389
            |||:|||.|...|.:...||.:.      .||.:.        ||||:..:||...:.|:|...:
  Fly   385 GRRILLLASGISMAISTTAIGVY------FFLQKQDAAQVVSLGWLPVASLCLFIIMFSIGYGPV 443

  Fly   390 IFIIIIELLPAKIRSIGTSLSMATFSGFIFVALKIYPTMIYDQGLAATMFMSAGMCLFGFIVLGL 454
            .::::.||....|:....||:..:.....||..|.:..:....|:..|.::.||:.:.|.|.:..
  Fly   444 PWLMMGELFATDIKGFAGSLAGTSNWLLAFVVTKTFVNLNDGLGIGGTFWLFAGLTVVGVIFVYF 508

  Fly   455 FLPETKGK 462
            .:||||||
  Fly   509 AVPETKGK 516

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14606	NP_001334690.1	None
CG10960	NP_648605.1	MFS_1	117..474	CDD:284993	106/382 (28%)
CG10960	NP_648605.1	MFS	118..508	CDD:119392	115/415 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45444286
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D430696at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR48021
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
	6	5.850