DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG14606 and CG8249

DIOPT Version :9

Sequence 1:	NP_001334690.1	Gene:	CG14606 / 40866	FlyBaseID:	FBgn0037485	Length:	466	Species:	Drosophila melanogaster
Sequence 2:	NP_001246349.1	Gene:	CG8249 / 36742	FlyBaseID:	FBgn0034045	Length:	521	Species:	Drosophila melanogaster

Alignment Length:	466	Identity:	127/466 - (27%)
Similarity:	217/466 - (46%)	Gaps:	37/466 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 RWQFIATMTVHIMTLTHGIAVGWLSPSLRLLASDESPLGDPLTITQASWVGSLIGLGSLTGNIIF 81
            |.|.||.:..::...:.|:.:...:.:|..|.....|:  .|..:||||..|:..|.:..|.::.
  Fly    43 RRQVIAVILANVGVFSTGMTLAMPTATLHQLKDTTEPV--HLNDSQASWFASVNALSAPIGGLLS 105

  Fly    82 GLLLDRLGRKVCMYFLAIPNMIYWILI----YSAQDVTY--LYAGRFLAGMSGGGCYVVLPIFIA 140
            |.||||:|||..:..|.:..::.|||:    .|.|:..:  |...||:.|:..|.......::.|
  Fly   106 GFLLDRIGRKKSLIVLNVLIILAWILLATPSESDQNAFFWQLIVSRFMLGVGMGLASAPPGVYAA 170

  Fly   141 EIADNSVRGALSSMAMMYVSIGMMVGFTLASYLPYYLMPCI-----IVAL-----PVVFMLSVIG 195
            ||:....||:|    ::..||.:..|.|:...:.|    ||     ::||     .:|.:|.|:.
  Fly   171 EISVPKTRGSL----ILGTSISVAGGITILYGIGY----CIRDDFRLIALICCGYQLVALLCVLP 227

  Fly   196 LSETPQYLLRRGRDDQAEKSFYFYKNLTPPTSSDKEASQHDAAKIEFDTFR--LQVLSGGVTESI 258
            |.|:..:||.:.|..:|::|..:::..   ..||:  ..|.....||...:  ||..:..|.||.
  Fly   228 LPESHCWLLSKKRVTEAKRSLNYFRGF---NKSDE--ITHPQVLEEFQLLQKSLQQRNTAVKESF 287

  Fly   259 SWRDFINVPTLKIFGLIFVLIICNQLSGSFAIFNYTSHIFAELGNNLDPNTSTIVVGAAQLVGIF 323
             ||:.......|...::..|....||:|.|.:..:...|..|.|..:||....:::|.|:|:...
  Fly   288 -WRNLHEPEVYKPLVILMSLFAFQQLTGIFVVIVFAVQISQEAGIEIDPFMCAVLIGLARLITTC 351

  Fly   324 SAVVLVDRLGRRVLLLTSMGGMGLGELAIALLKCFASDEFLNQNGWLPLVIMCLVACIASLGVIA 388
            ....:::..|||...:.|..||   .:.:.||...:..|.|.:..:||:|.:.....:::||:..
  Fly   352 PMGYILEWWGRRRAGIISTLGM---SVCMFLLAGHSQIEILKEVPYLPVVAIVGFIVLSTLGLYT 413

  Fly   389 LIFIIIIELLPAKIRSIGTSLSMATFSGFIFVALKIYPTMIYDQGLAATMFMSAGMCLFGFIVLG 453
            |.|.:|.||.|.|:|...:.|::|......||.||.||.:....|::....:...|.||..|.:.
  Fly   414 LPFFMISELFPQKVRGPASGLTVAVGMFISFVVLKTYPGIKEYLGMSNCFIIFGVMALFALIFVY 478

  Fly   454 LFLPETKGKLM 464
            |.||||:.:.:
  Fly   479 LALPETRRRTL 489

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14606	NP_001334690.1	None
CG8249	NP_001246349.1	MFS	49..479	CDD:119392	118/448 (26%)
CG8249	NP_001246349.1	Sugar_tr	60..496	CDD:278511	123/449 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45444498
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D430696at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR48021
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
	6	5.850