DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG14606 and Slc2a10

DIOPT Version :9

Sequence 1:	NP_001334690.1	Gene:	CG14606 / 40866	FlyBaseID:	FBgn0037485	Length:	466	Species:	Drosophila melanogaster
Sequence 2:	NP_001102433.1	Gene:	Slc2a10 / 366251	RGDID:	1306552	Length:	536	Species:	Rattus norvegicus

Alignment Length:	545	Identity:	115/545 - (21%)
Similarity:	198/545 - (36%)	Gaps:	170/545 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 LSPSLRLLASDESPLGD---------------PL-------TITQASWVGSLIGLGSLTGNIIFG 82
            |.|::..|.:..|.||.               ||       .:.|...||||: ||:...:::.|
  Rat     3 LGPTVLPLCASVSLLGGLTFGYELAVISGALLPLQLDFRLSCLEQELLVGSLL-LGAFLASLVGG 66

  Fly    83 LLLDRLGRKVCMYFLAIPNMIYWILIYSAQDVTYLYAGR----FLAGMSGGGCYVVLPIFIAEIA 143
            .|:|..||:..:....:..:...:::..|..:.:|..||    |...:|...|.    |:::|:.
  Rat    67 FLIDCYGRRRAILGSNVVLLAGSLILGLAGSLPWLLLGRSSVGFAISLSSMACC----IYVSELV 127

  Fly   144 DNSVRGALSSMAMMYVSIGMMVGFTLASYLPYYL---------------MPCIIVALPVVFMLSV 193
            ....||.|.|:    ..:|:.||...:..|.|.|               .|.::.:|.:.|
  Rat   128 GPRQRGVLVSL----YEVGITVGILFSYGLNYVLAGSPWGWRHMFGWAAAPALLQSLSLFF---- 184

  Fly   194 IGLSETPQYLLRRGRDDQAEKSFYFYKNLTPPTSSDKEASQHDAAKIEF---DTFRLQVLSGGVT 255
                      |..|.:..|.:     ::|.|....  |.|:....|.::   |.||.|   .|:
  Rat   185 ----------LPAGAEGTAAR-----QDLIPLQGG--ETSKLGLVKAQYTFLDLFRAQ---DGM- 228

  Fly   256 ESISWRDFINVPTLKIFGLIFVLIICNQLSGSFAIFNYTSHIFAELG--NNLDPNTSTIVVGAAQ 318
                |       :..:.||  .|::..||:|...:..|.|.||..:|  .......:::.:|..:
  Rat   229 ----W-------SRTVVGL--GLVLFQQLTGQPNVLYYASTIFRSVGFHGGSSAVLASVGLGTVK 280

  Fly   319 LVGIFSAVVLVDRLGRRVLLLT-------SMGGMGLGELAIAL---LKCFASDE----------- 362
            :|....|..||||:|||.|||:       |:.|:||...|::|   ..|.|:..
  Rat   281 VVATLIATGLVDRVGRRALLLSGCALMALSVSGIGLVSFAVSLDSGPSCLATSNTSQQVDLPQTP 345

  Fly   363 ----------FLNQNG--------------------------------------------WLPLV 373
                      .|:.:|                                            |..||
  Rat   346 GLLVRTSLPPVLHTSGDQGQPVRSVTERPIHPVITASLGPALNIDSSVPTSPIPEHTLLCWSALV 410

  Fly   374 IMCLVACIASLGVIALIFIIIIELLPAKIRSIGTSL-SMATFSGFIFVALKIYPTMIYDQGLAAT 437
            .|.:.....|.|...:.::::.|:.|.:||....:. |...::..:|::|. :..:|...|||.|
  Rat   411 CMMVYVSAFSFGFGPVTWLVLSEIYPVEIRGRAFAFCSSFNWAANLFISLS-FLDLIGAIGLAWT 474

  Fly   438 MFMSAGMCLFGFIVLGLFLPETKGK 462
            ..:.....:.|...:.|.:|||||:
  Rat   475 FLLYGLTAVLGLAFIYLLVPETKGQ 499

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14606	NP_001334690.1	None
Slc2a10	NP_001102433.1	Sugar_tr	11..508	CDD:278511	112/537 (21%)
Slc2a10	NP_001102433.1	MFS	14..>330	CDD:119392	83/362 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166337854
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53651
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.750