DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14606 and Slc2a1

DIOPT Version :9

Sequence 1:	NP_001334690.1	Gene:	CG14606 / 40866	FlyBaseID:	FBgn0037485	Length:	466	Species:	Drosophila melanogaster
Sequence 2:	NP_620182.1	Gene:	Slc2a1 / 24778	RGDID:	3704	Length:	492	Species:	Rattus norvegicus

Alignment Length:	436	Identity:	104/436 - (23%)
Similarity:	190/436 - (43%)	Gaps:	64/436 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    57 PLTITQASWVGS--LIGLGSLTGNIIFGLLLDRLGRKVCMYFLAIPNMIYWILI-YS--AQDVTY 116
            |.|.....|..|  :..:|.:.|:...||.::|.||:..|..:.:...:..:|: :|  .:....
  Rat    57 PSTTLTTLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLMMNLLAFVSAVLMGFSKLGKSFEM 121

  Fly   117 LYAGRFLAGMSGGGCYVVLPIFIAEIADNSVRGALSSMAMMYVSIGMMVG--FTLASYLPYY-LM 178
            |..|||:.|:..|.....:|:::.|::..::||||.::..:.:.:|:::.  |.|.|.:... |.
  Rat   122 LILGRFIIGVYCGLTTGFVPMYVGEVSPTALRGALGTLHQLGIVVGILIAQVFGLDSIMGNADLW 186

  Fly   179 PCIIVALPVVFMLSVIGL---SETPQYLLRRGRDDQAEKSFYFYKNLTPPTSSDKEASQHDAAKI 240
            |.::..:.:..:|..|.|   .|:|::||....::...||.......|...:.|.:..:.:..::
  Rat   187 PLLLSVIFIPALLQCILLPFCPESPRFLLINRNEENRAKSVLKKLRGTADVTRDLQEMKEEGRQM 251

  Fly   241 EFDTFRLQVLSGGVTESISWRDFINVPTLKIFGLIFVLIICNQLSGSFAIFNYTSHIFAELGNNL 305
            ..:. ::.:|.  :..|.::|.    |.|    :..||.:..||||..|:|.|::.||.:.|..
  Rat   252 MREK-KVTILE--LFRSPAYRQ----PIL----IAVVLQLSQQLSGINAVFYYSTSIFEKAGVQ- 304

  Fly   306 DPNTSTIVVGAAQLVGIFSAVVLVDRLGRRVLLLTSMGGMG----LGELAIALLKCFASDEFLNQ 366
            .|..:||..|.........::.:|:|.|||.|.|..:.||.    |..:|:|||:         |
  Rat   305 QPVYATIGSGIVNTAFTVVSLFVVERAGRRTLHLIGLAGMAGCAVLMTIALALLE---------Q 360

  Fly   367 NGWLPLVIMCLVACIASLGVIALI--------FIIIIELL-----PAKIRSIGTSLSMATF-SGF 417
            ..|     |..::.:|..|.:|..        :.|:.||.     ||.:...|.|...:.| .|.
  Rat   361 LPW-----MSYLSIVAIFGFVAFFEVGPGPIPWFIVAELFSQGPRPAAVAVAGFSNWTSNFIVGM 420

  Fly   418 IFVALKIYPTMIYDQGLAATMFMSAGMCLFGFIVLGLF-LPETKGK 462
            .|        ...:|.....:|:...:.|..|.:...| :|||||:
  Rat   421 CF--------QYVEQLCGPYVFIIFTVLLVLFFIFTYFKVPETKGR 458

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14606	NP_001334690.1	None
Slc2a1	NP_620182.1	MFS_GLUT_Class1	14..458	CDD:340989	103/434 (24%)
		Monosaccharide binding. /evidence=ECO:0000250\|UniProtKB:P11166	282..288		4/5 (80%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	468..492
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166337861
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.840