Protein Alignment CG14606 and Slc2a2

DIOPT Version :10

• Sequence 1: NP_001334690.1
• Gene: CG14606 / 40866
• FlyBaseID: FBgn0037485
• Length: 466
• Species: Drosophila melanogaster
• Sequence 2: NP_112474.2
• Gene: Slc2a2 / 20526
• MGIID: 1095438
• Length: 523
• Species: Mus musculus
• Alignment Length: 492
• Identity: 117/492 - (23%)
• Similarity: 199/492 - (40%)
• Gaps: 144/492 - (29%)

  Fly    25 TVHIMTLTHGIAV--------------GWLSPSLRLLASDESPLGDPLTITQASWVGSLIGLGSL 75
            :.||:|:...::|              ||              |||.|...:|....:.:   ||
Mouse    88 SAHIVTMLWSLSVSSFAVGGMVASFFGGW--------------LGDKLGRIKAMLAANSL---SL 135

  Fly    76 TGNIIFGLLLDRLGRKVCMYFLAIPNMIYWILIYSAQDVTYLYAGRFLAGMSGGGCYVVLPIFIA 140
            ||.::.|          |..|...     ..||.:.:.|:.||.| .::|:        :|::|.
Mouse   136 TGALLMG----------CSKFGPA-----HALIIAGRSVSGLYCG-LISGL--------VPMYIG 176

  Fly   141 EIADNSVRGALSSMAMMYVSIGMMV------GFTLASYLPYYLM------PCIIVALPVVFMLSV 193
            |||..::||||.::..:.:..|:::      .|.|.:...::::      |.::..|.::|
Mouse   177 EIAPTTLRGALGTLHQLALVTGILISQIAGLSFILGNQDHWHILLGLSAVPALLQCLLLLF---- 237

  Fly   194 IGLSETPQYL-LRRGRDDQAEKSFYFYKNLTPPTSSDKEASQHDAAKIEFDTFRLQVLSGGVTES 257
              ..|:|:|| ::...:.:|:||.   |.|.......|:.::....|.|..|.:
Mouse   238 --CPESPRYLYIKLEEEVRAKKSL---KRLRGTEDVTKDINEMKKEKEEASTEQ----------- 286

  Fly   258 ISWRDFINVPTLKIFG---------LIFVLIICNQLSGSFAIFNYTSHIFAELGNNLDPNTSTIV 313
                   .|..:::|.         :..:|.:..|.||...||.|::.||...|.: .|..:||.
Mouse   287 -------KVSVIQLFTDANYRQPILVALMLHMAQQFSGINGIFYYSTSIFQTAGIS-QPVYATIG 343

  Fly   314 VGAAQLVGIFSAVVLVDRLGRRVLLLTSMGGMG----LGELAIALLKCFASDEFLNQNGWLPLVI 374
            |||..::....:|:||::.|||.|.||.|.||.    ...:.:.||..||         |:..|.
Mouse   344 VGAINMIFTAVSVLLVEKAGRRTLFLTGMIGMFFCTIFMSVGLVLLDKFA---------WMSYVS 399

  Fly   375 MCLVACIASLGVIALIFIIIIELLP--------AKIRSIG---TSLSMATFSGFI--FVALKIYP 426
            |..:          .:|:...|:.|        |:..|.|   |:|::|.||.::  ||....:
Mouse   400 MTAI----------FLFVSFFEIGPGPIPWFMVAEFFSQGPRPTALALAAFSNWVCNFVIALCF- 453

  Fly   427 TMIYDQGLAATMFMSAGMCLFGFIVLGLF-LPETKGK 462
            ..|.|.......|:.||:.|. |.:...| :||||||
Mouse   454 QYIADFLGPYVFFLFAGVVLV-FTLFTFFKVPETKGK 489

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14606	NP_001334690.1	MFS_GLUT6_8_Class3_like	20..466	CDD:340916	117/492 (24%)
Slc2a2	NP_112474.2	MFS_GLUT_Class1	12..489	CDD:340989	115/490 (23%)