DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14606 and Slc2a9

DIOPT Version :9

Sequence 1:	NP_001334690.1	Gene:	CG14606 / 40866	FlyBaseID:	FBgn0037485	Length:	466	Species:	Drosophila melanogaster
Sequence 2:	NP_001095884.1	Gene:	Slc2a9 / 117591	MGIID:	2152844	Length:	538	Species:	Mus musculus

Alignment Length:	439	Identity:	123/439 - (28%)
Similarity:	192/439 - (43%)	Gaps:	61/439 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    56 DPLTITQA-SWVGSLIGLGSLTGNIIFGLLLDRLGRKVCMYF---LAIPNMIYWILIYSAQDVTY 116
            ||.|:|.. |...|:..:|.|.|.::..::...||||..:..   .||...:.......|.....
Mouse    83 DPDTLTLLWSVTVSIFAIGGLVGTLMVKMIGKFLGRKSTLLVNNGFAISAALLMACSLRAGTFEM 147

  Fly   117 LYAGRFLAGMSGGGCYVVLPIFIAEIADNSVRGALSSMAMMYVSIGMMVGFTLA--------SYL 173
            |..|||:.|:.||.....||:::.||:...:||:|..:..:::.||:..|..|.        |..
Mouse   148 LIVGRFIMGVDGGIALSALPMYLNEISPKEIRGSLGQVTAIFICIGVFSGQLLGLPELLGRESTW 212

  Fly   174 PYYLMPCIIVALPVVFMLSVIGLSETPQYLLRRGRDDQ-AEKSFYFYKNLTPPTSSDKEASQHDA 237
            ||.....|:.||  |.:.|:..|.|:|:|||....|:. |.|:|..:......:...:||...
Mouse   213 PYLFGVIIVPAL--VQLASLPFLPESPRYLLFEKHDEAGAMKAFQTFLGKADVSQELEEALAE-- 273

  Fly   238 AKIEFDTFRLQVLSGGVTESISWRDFINVPTLKIFGLIFVLIICNQLSGSFAIFNYTSHIFAELG 302
            ::::.:...:.||.......:.|:....:.|:..:          ||.|..||:.||:.||.:.|
Mouse   274 SRVQRNLRLVSVLELLRAPFVRWQVITVIITMASY----------QLCGLNAIWFYTNSIFGKAG 328

  Fly   303 NNLD--PNTSTIVVGAAQLVGIFSAVVLVDRLGRRVLLLTSMGGMGLGELAIALLKCFASDEFLN 365
            ...|  |..:....|...|..|||.:| ::|||||.||:   ||.||..|....|.  |:....:
Mouse   329 IPQDKIPYITLSTGGIETLAAIFSGLV-IERLGRRPLLI---GGFGLMALFFGTLT--ATLTLQD 387

  Fly   366 QNGWLP-LVIMCLVACIASL--GVIALIFIIIIELL-----PAKIRSIGTSLSMATFS-----GF 417
            |..|:| |.|:|::|.|||.  |...:.||:..|..     ||.....||...::.|:     .|
Mouse   388 QAPWVPYLSIVCILAIIASFCSGPGGIPFILTGEFFQQSERPAAFMIAGTVNWLSNFAVGLLFPF 452

  Fly   418 IFVALKIYPTMIYDQGLAATMFMSAGMCLFGFIVLGLFLPETKGKLMTH 466
            |..:|..|..:::           |.:|:.|.......|||||.:  ||
Mouse   453 IQKSLDSYCFLVF-----------ATICIAGATYFYFVLPETKNR--TH 488

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14606	NP_001334690.1	None
Slc2a9	NP_001095884.1	MFS_GLUT_Class2	40..491	CDD:340990	123/439 (28%)
Slc2a9	NP_001095884.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	495..538
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167834320
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.840