DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG14606 and slc2a3b

DIOPT Version :9

Sequence 1:	NP_001334690.1	Gene:	CG14606 / 40866	FlyBaseID:	FBgn0037485	Length:	466	Species:	Drosophila melanogaster
Sequence 2:	XP_002667169.2	Gene:	slc2a3b / 100330897	ZFINID:	ZDB-GENE-121031-5	Length:	534	Species:	Danio rerio

Alignment Length:	499	Identity:	122/499 - (24%)
Similarity:	213/499 - (42%)	Gaps:	96/499 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 TVHIMTLTHGIAVGWL-SPSLRL--------LASDESPLGDPLTITQASWVGSLIGLGSLTGNII 80
            |..|.:|..|..:|.: :|.:::        |.....|:.|....|..|...::...|.:.|::.
Zfish    22 TAVIGSLQFGYNIGVINAPDVKVQNFFRNVTLVRTGEPMDDYTVTTLWSVAVAIFNFGGMIGSLS 86

  Fly    81 FGLLLDRLGRKVCMYFLAIPNMIYWIL-----IYSAQDVTYLYAGRFLAGMSGGGCYVVLPIFIA 140
            .|.|:::||.:..|....|..:|...|     |.|:.::  |..||.:.|:..|....:.|:::.
Zfish    87 VGALVNKLGGRKSMLLSNILALIGGGLMGLSSICSSYEL--LIVGRLVIGVFCGLSTGLTPMYVG 149

  Fly   141 EIADNSVRGALSSMAMMYVSIGMMVG--FTLASYL------PYYL----MPCIIVALPVVFMLSV 193
            |||..::|||..::..:.|.||::|.  ..|.|.|      |..|    :|.:|.::.::|.|
Zfish   150 EIAPTALRGAFGTLHQLGVVIGILVAQILGLESLLGSQTLWPLLLALTALPAVIQSIMLIFCL-- 212

  Fly   194 IGLSETPQYLL-RRGRDDQAEKSFYFYKNLTPPTSSDKEASQHDAAKIEFDTFRLQVLSGGVTES 257
                |:|:||| ...::|:|.::....:.     .||.|   .|..:::.:..::
Zfish   213 ----ESPRYLLISLNKEDEARQALTSLRG-----HSDVE---DDIREMKDEAMKM---------- 255

  Fly   258 ISWRDFINVPTL-------KIFGLIFVLIICNQLSGSFAIFNYTSHIFAELGNNLDPNTSTIVVG 315
             |....:::|.|       :...:..:|.:..||||..|:..|::.||...|.. :|..:||.:|
Zfish   256 -SMEKRVSIPELFRNPAYRQPIIIAIILQLSQQLSGINAVMYYSTEIFRNAGIT-EPVFATIGMG 318

  Fly   316 AAQLVGIFSAVVLVDRLGRRVLLLTSMGGMGLGELAIALLKCFASDEF----LNQNGWL------ 370
            ....|....::.||:|.|||.|.|..:.||....|.:.:.......|.    |.|||..
Zfish   319 VVNTVFTVVSLFLVERAGRRTLHLIGLTGMTFCVLLVTISLKLVDSEIEKAKLLQNGTAIIDSAS 383

  Fly   371 ---------PLVIMCLVACIAS--LGVIALIFIIIIELL-----PAKIRSIGTSLSMATFSGFIF 419
                     .|.|:.:...:||  :|...:.:.|:.||.     ||.:...|.....|:|    .
Zfish   384 PSEGISTVKVLAILAVFGFVASFEMGPGPIPWFIVAELFAQGPRPAAMAVAGCCNWTASF----L 444

  Fly   420 VALKIYPTMIYDQGLAATMFMSAGMCLFGFIVLGLF-LPETKGK 462
            |.| ::|  |..:.:.|.:|:...:.|..|||...| :|||||:
Zfish   445 VGL-LFP--ILSKKIGAYVFIIFLILLVVFIVFTYFRVPETKGR 485

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14606	NP_001334690.1	None
slc2a3b	XP_002667169.2	Sugar_tr	19..494	CDD:278511	122/499 (24%)
slc2a3b	XP_002667169.2	MFS	66..479	CDD:119392	108/447 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170577126
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.840