Protein Alignment lap and Picalm

DIOPT Version :10

• Sequence 1: NP_001163538.1
• Gene: lap / 40863
• FlyBaseID: FBgn0086372
• Length: 788
• Species: Drosophila melanogaster
• Sequence 2: XP_006229731.1
• Gene: Picalm / 89816
• RGDID: 621054
• Length: 686
• Species: Rattus norvegicus
• Alignment Length: 828
• Identity: 320/828 - (38%)
• Similarity: 424/828 - (51%)
• Gaps: 190/828 - (22%)

  Fly     3 MAGQTINDRLLAARHSLAGQGLAKSVCKATTEECIGPKKKHLDYLVHCTNEPNVSIPHLANLLIE 67
            |:||::.||:.||:||:.|..::|:||||||.|.:||||||||||:.||||.||:||.||:.|.|
  Rat     1 MSGQSLTDRITAAQHSVTGSAVSKTVCKATTHEIMGPKKKHLDYLIQCTNEMNVNIPQLADSLFE 65

  Fly    68 RSQNANWVVVYKSLITTHHLMAYGNERFMQYLASSNSTFNLSSFLDKGTVQDGGMGVPGGRMGYD 132
            |:.|::||||:||||||||||.||||||:|||||.|:.||||:||||           .|..|||
  Rat    66 RTTNSSWVVVFKSLITTHHLMVYGNERFIQYLASRNTLFNLSNFLDK-----------SGLQGYD 119

  Fly   133 MSPFIRRYAKYLNEKSLSYRAMAFDFCKVKRGKEEGSLRSMNAEKLLKTLPVLQAQLDALLEFDC 197
            ||.|||||::|||||::|||.:||||.||||| .:|.:|:||.||||||:|::|.|:||||:|:.
  Rat   120 MSTFIRRYSRYLNEKAVSYRQVAFDFTKVKRG-ADGVMRTMNTEKLLKTVPIIQNQMDALLDFNV 183

  Fly   198 QSNDLSNGVINMSFMLLFRDLIRLFACYNDGIINLLEKYFDMNKKHARDALDLYKKFLVRMDRVG 262
            .||:|:|||||.:|||||:|.|||||.||:||||||||||||.|...::.||:|||||.||.|:.
  Rat   184 NSNELTNGVINAAFMLLFKDAIRLFAAYNEGIINLLEKYFDMKKNQCKEGLDIYKKFLTRMTRIS 248

  Fly   263 EFLKVAENVGIDKGDIPDLTKAPSSLLDALEQHLATLEGRKVSAANTPTQSSSNQRNVKSAVSAL 327
            |||||||.||||:||||||::||||||||||||||:|||:|:.    .:.::|....:.:|||:|
  Rat   249 EFLKVAEQVGIDRGDIPDLSQAPSSLLDALEQHLASLEGKKIK----DSTAASRATTLSNAVSSL 309

  Fly   328 SSTSSAFGTAAASSKFDTTNGIDEQLKAQVLAEEEAAMNQYKSK---------------VSSPTS 377
            :||..:.            ..:||:.|...|.||:|.:...|.:               .:||.|
  Rat   310 ASTGLSL------------TKVDEREKQAALEEEQARLKALKEQRLKELAKKPHTSLTTAASPVS 362

  Fly   378 SGAAGASAALTNPFLSSPPAAQAGQPIVDLFGAASAQPAAAAAATKASDDLLQLGNPFADMFDAS 442
            :.|.|...|                |.:|:|    :.|:::.:.:|..:|||.|..|
  Rat   363 TSAGGIMTA----------------PAIDIF----STPSSSNSTSKLPNDLLDLQQP-------- 399

  Fly   443 GGGAAAVGATGFNGASVSSAAATNAFVSDSNFSSVFGNTEPAASTSLP--NPFFDDMSLPQIPLP 505
                     |........|||...|    |.:...|..|..|...::|  |||....| ..:.||
  Rat   400 ---------TFHPSVHAMSAAPQVA----STWGDPFSATLDAVDDAIPSLNPFLTKSS-GDVHLP 450

  Fly   506 AESVAAPFGNN-------INFMDQQL-QQQQQAALYVQQQQQQQLQLQQQQHRPQLPQQQAILTP 562
            ..|..:.|...       :.|....: |....|.|.|.                   .:......
  Rat   451 ISSDVSTFTTRTPTHEMFVGFSPSPVTQPHPSAGLNVD-------------------FESVFGNK 496

  Fly   563 SMSAAQFPPGFDALGDVLKPASASNNSNQMNVVAAGYSSNSSSILALQQQQHQQHQQQHQHQLNQ 627
            |.:.|....|||.||.:|||..||.|
  Rat   497 STNVAVDSGGFDELGGLLKPTVASQN--------------------------------------- 522

  Fly   628 QQQQQPPA--GTGKIITGDLDSSLMSLVDNLNINKTASAKPVQWNSP-KNTAKPGANWTPQ--PM 687
              |..|.|  ...|:::.||||||.:||.||.|....:...|.|:.| :.....|:||.|:  |.
  Rat   523 --QSLPVAKLAPNKLVSDDLDSSLANLVGNLGIGNGTTKNDVSWSQPGEKKLTGGSNWQPKVAPT 585

  Fly   688 AATTGA--------GYRP--MAHGMTVSPAPITINHPYIHASYPVM--PNYMQGMPVMGQPSMMG 740
            .|.:.|        .|.|  ||:..|.....|....|....|.|||  |..:...|||..|:..|
  Rat   586 TAWSAATMNGMHFPQYAPPVMAYPATTPTGMIGYGIPPQMGSVPVMTQPTLIYSQPVMRPPNPFG 650

  Fly   741 GQAAAPLTGVQPTMMAAPHSNATGIMQPIQPTQNGSNKGVPLDPFGAL 788
                 |:.|.|   ::|..|          |:::..::....|||..|
  Rat   651 -----PVPGAQ---LSAASS----------PSRHSPHRAAGKDPFAEL 680

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lap	NP_001163538.1	ANTH	23..296	CDD:400137	184/272 (68%)
Picalm	XP_006229731.1	ANTH	24..282	CDD:400137	184/269 (68%)