DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment lap and AT1G14910

DIOPT Version :9

Sequence 1:	NP_001163538.1	Gene:	lap / 40863	FlyBaseID:	FBgn0086372	Length:	788	Species:	Drosophila melanogaster
Sequence 2:	NP_172944.1	Gene:	AT1G14910 / 838056	AraportID:	AT1G14910	Length:	692	Species:	Arabidopsis thaliana

Alignment Length:	799	Identity:	175/799 - (21%)
Similarity:	289/799 - (36%)	Gaps:	218/799 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 SVCKATTE-ECIGPKKKHLDYLVHCTN--EPNVSIPHLANLLIER-SQNANWVVVYKSLITTHHL 87
            ::.|||.. || .||.:||..:...|:  .|...:.:..:.|..| .:..||.|..|:|:..|.|
plant    35 AIVKATNHVEC-PPKDRHLRKIFLATSAIRPRADVAYCIHALSRRLHKTRNWTVALKALLVIHRL 98

  Fly    88 MAYGNERFMQYLASSNSTFNLSSFLDKGTV-QDGGMGVPGGRMGYDMSPFIRRYAKYLNEKSLSY 151
            :..|:..|.:         .|.:|..||.: |..........:.:|.|.::|.||.:|.|:...:
plant    99 LRDGDPTFRE---------ELLNFSQKGRIMQISNFKDDSSPVAWDCSGWVRTYALFLEERLECF 154

  Fly   152 RAMAFD-----FCKVKRGKEEG--SLRSMNAEKLLKTLPVLQAQLDALLEFDCQSNDLSNGVINM 209
            |.:.:|     ..||..|:|:|  ..|.::.||||:.||.||..|..|:....:.....|.:|..
plant   155 RVLKYDIEAERLPKVSPGQEKGYSKTRDLDGEKLLEQLPALQQLLHRLIGCKPEGAAKHNHIIQY 219

  Fly   210 SFMLLFRDLIRLFACYNDGIINLLEKYFDMNKKHARDALDLYKKFLVRMDRVGEFLKVAENVGID 274
            :..|:.::..:::...|:|||||:||:|:|.:..|..||::||:..::...:..|.:|.:.:.:.
plant   220 ALSLVLKESFKVYCAINEGIINLVEKFFEMPRHEAIKALEIYKRAGLQAGNLSAFYEVCKGLELA 284

  Fly   275 KG-DIPDLTKAPSSLLDALEQHLATLEGRKVSAANTPTQSSSNQRNVKSAVSALSSTSSAFGTAA 338
            :. ..|.|.:.|.|.|..:|:::               :.:....:|.|....|:.|..
plant   285 RNFQFPVLREPPQSFLTTMEEYM---------------RDAPQMVDVTSGPLLLTYTPD------ 328

  Fly   339 ASSKFDTTNGIDEQLKAQVLAEEEAAMNQYKSKVSSPTSSGAAGASAALTNPFLSSPPAAQAGQP 403
                    :|         |..|:...:..:.:.|||:.|....:..  |.....|||:.:..|.
plant   329 --------DG---------LTSEDVGPSHEEHETSSPSDSAVVPSEE--TQLSSQSPPSVETPQN 374

  Fly   404 IV---DLFGAASAQPAAAAAATKASDDLLQLGNPFADMFDASGGGAAAVGATGFNGASVSS---- 461
            .:   ||.|.....|...|...:.:..|..:.|. .|....|.|.|..:..:|:..|.|::
plant   375 FIDTDDLLGLHDDTPDPLAILDQNALALALVSND-VDSSPFSFGQARDLDPSGWELALVTTPSND 438

  Fly   462 -AAATNAFVSDSNFSSVFGNTEPAASTSLPNPFFDDMSLPQIPLPAESVAAPFGNNINFMDQQLQ 525
             :|||...::.            ...|...|..:||.:|.....||..|  |..|.....|
plant   439 ISAATERQLAG------------GLDTLTLNSLYDDGALRAAQQPAYGV--PASNPFEVQD---- 485

  Fly   526 QQQQAALYVQQQQQQQLQLQQQQHRPQLPQQQAILTPSMSAAQFPPGFDALGDVLKPASASNNSN 590
                  |:                                         |..|.:.|.||.||.
plant   486 ------LF-----------------------------------------AFSDSVSPPSAVNNP- 502

  Fly   591 QMNVVAAGYSSNSSSILALQQQQHQQHQQQHQHQLNQQQQQQPPAGTGKIITGDLDSSLMSLVDN 655
                            ..|.:..:  |||:.|.||........|.|         |.....:|
plant   503 ----------------FGLYEPTY--HQQEQQPQLQVAPSPANPFG---------DFGEFPIV-- 538

  Fly   656 LNINKTASAKPVQWNSPKNTAKPGANWTPQPMAA---TTGAGYRPMAHGMTVSPAPITINHPYIH 717
                      ||  :.|::|...||  .|.|::.   |||.|..|:   :.|:..|.|.    ..
plant   539 ----------PV--SEPQSTTSFGA--FPVPVSEPSNTTGFGEIPV---VPVTEPPNTT----AF 582

  Fly   718 ASYPVMPNYMQGMPVMGQPSMMGGQAAAPLT-----------GVQPTMMAAPHSNATG------- 764
            ..:||:|        :.:|..:.|..|.|:|           |..|.:..:...|.||
plant   583 GEFPVVP--------VSEPQNITGFGALPVTPASEPSNTTGFGEFPVVSVSAPQNTTGFGALPVI 639

  Fly   765 -IMQPIQPTQNGSNKGVPL 782
             :.:|.:.|..|....||:
plant   640 PVSEPSKTTGLGEFPVVPV 658

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lap	NP_001163538.1	ANTH	21..298	CDD:284961	78/283 (28%)
lap	NP_001163538.1	Amelogenin	694..>773	CDD:197891	19/97 (20%)
AT1G14910	NP_172944.1	ANTH	29..310	CDD:284961	78/299 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	111	1.000	Domainoid score	I2074
eggNOG	1	0.900	-	-		E1_KOG0251
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	115	1.000	Inparanoid score	I2025
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		oto3307
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22951
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X389
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	10	9.920