DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lap and AT5G57200

DIOPT Version :9

Sequence 1:	NP_001163538.1	Gene:	lap / 40863	FlyBaseID:	FBgn0086372	Length:	788	Species:	Drosophila melanogaster
Sequence 2:	NP_200530.1	Gene:	AT5G57200 / 835826	AraportID:	AT5G57200	Length:	591	Species:	Arabidopsis thaliana

Alignment Length:	647	Identity:	143/647 - (22%)
Similarity:	244/647 - (37%)	Gaps:	147/647 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 GLAK----------SVCKATTEECIGPKKKHLDYLVHCTN--EPNVSIPHLANLLIER-SQNANW 74
            ||||          ::.|||......||::|:..:...|:  :|...:.:..:.|.:| |:..||
plant    21 GLAKVNSEFKDLDIAIVKATNHVESPPKERHVRKIFSATSVIQPRADVAYCIHALSKRLSKTRNW 85

  Fly    75 VVVYKSLITTHHLMAYGNERFMQYL---ASSNSTFNLSSFLDKGTVQDGGMGVPGGRMGYDMSPF 136
            ||..|.||..|..:..|:..|.:.|   :.......:|:|.|..:           .:.:|.|.:
plant    86 VVAMKVLIVIHRTLREGDPTFREELLNYSHRRHILRISNFKDDTS-----------PLAWDCSAW 139

  Fly   137 IRRYAKYLNEKSLSYRAMAFDFCKVKRGKEEGS------LRSMNAEKLLKTLPVLQAQLDALLEF 195
            :|.||.:|.|:...||.:.:|....:..|..|:      .|.::.|.||:.||.||..|..|:..
plant   140 VRTYALFLEERLECYRVLKYDIEAERLPKASGAASKTHRTRMLSGEDLLEQLPALQQLLYRLIGC 204

  Fly   196 DCQSNDLSNGVINMSFMLLFRDLIRLFACYNDGIINLLEKYFDMNKKHARDALDLYKKFLVRMDR 260
            ..:....||.:|..:..|:.::..:::...|||||||::.:|:|::..|..||::||:...:.:.
plant   205 QPEGAAYSNYLIQYALALVLKESFKIYCAINDGIINLVDMFFEMSRHDAVKALNIYKRAGQQAEN 269

  Fly   261 VGEF------LKVAENVGIDKGDIPDLTKAPSSLLDALEQHLATLEGRKVSAANTPTQSSSNQRN 319
            :.||      |::|.|.     ..|.|.:.|.|.|..:|:::           ....||.|.|:.
plant   270 LAEFYDYCKGLELARNF-----QFPTLRQPPPSFLATMEEYI-----------KEAPQSGSVQKK 318

  Fly   320 VKSAVSALSSTSSAFGTAAASSKFDTTNGIDEQLKAQVLAEEEAAMNQYKSKVSSPTSSGAAGAS 384
            ::...................::.:..|...|..:..:..|||....:.:.:.:.|:
plant   319 LEYQEKEEEEQEQEEEQPEEPAEEENQNENTENDQPLIEEEEEEPKEEIEVEEAKPS-------- 375

  Fly   385 AALTNPFLSSPPAAQAGQPIVDLFGAASAQPAAAAAATKASDDLLQLG--NPFADMFDASGGGAA 447
                              |::|                  :||||.|.  ||.|...:.:...:.
plant   376 ------------------PLID------------------TDDLLGLHEINPKAAEIEQNNAFSL 404

  Fly   448 AVGATGF------NGASVSSAAATN---AFVSDSNFSSVFGNTEPAASTSLPNPF---------F 494
            |:...|.      |..|:..|..:.   |.|:..|.::...|..|..:|.|...|         .
plant   405 AIYPPGHETSAPSNSLSLIEAGGSGWELALVTPQNNNNNNNNPRPVIATKLGGGFDNLLLDSLYE 469

  Fly   495 DDMSLPQIPLP---------------AESVAAPFG--NNINFMDQQLQQQQQAALYVQQQQQQQL 542
            ||.:..||.|.               |.|...|||  .:...|...:.......:.:||||...:
plant   470 DDTARRQIQLTNAGYGFGATAIPGALASSNPNPFGVQQDPFAMSNNMAPPTNVQMAMQQQQMMMM 534

  Fly   543 QLQQQQHRPQLPQQQAILTPSMSAAQFPPGFDALGD--VLKPASASNNSNQMNVVAAGYSSN 602
            ..|...:....|......:|:.|.:..|..|   ||  :..||..|:.:.|.      ||.|
plant   535 NNQSPYNNNYSPYHHHQFSPNPSTSSSPNPF---GDPFLALPAPPSSTTQQQ------YSPN 587

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lap	NP_001163538.1	ANTH	21..298	CDD:284961	80/302 (26%)
lap	NP_001163538.1	Amelogenin	694..>773	CDD:197891
AT5G57200	NP_200530.1	ANTH	34..307	CDD:336756	76/299 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	111	1.000	Domainoid score	I2074
eggNOG	1	0.900	-	-		E1_KOG0251
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	115	1.000	Inparanoid score	I2025
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001047
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR22951
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X389
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	10	9.920