DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment lap and AT2G01600

DIOPT Version :9

Sequence 1:	NP_001163538.1	Gene:	lap / 40863	FlyBaseID:	FBgn0086372	Length:	788	Species:	Drosophila melanogaster
Sequence 2:	NP_565267.1	Gene:	AT2G01600 / 814689	AraportID:	AT2G01600	Length:	571	Species:	Arabidopsis thaliana

Alignment Length:	597	Identity:	132/597 - (22%)
Similarity:	222/597 - (37%)	Gaps:	168/597 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 SVCKATTE-ECIGPKKKHLDYLVHCTN--EPNVSIPHLANLLIER-SQNANWVVVYKSLITTHHL 87
            ::.|||.. || .||.:||..:...|:  .....:.:..:.|..| .:..||.|..|:||..|.|
plant    35 AIVKATNHVEC-PPKDRHLRKIFAATSVTRARADVAYCIHALSRRLHKTRNWTVALKTLIVIHRL 98

  Fly    88 MAYGNERFMQYL---ASSNSTFNLSSFLDKGTVQDGGMGVPGGRMGYDMSPFIRRYAKYLNEKSL 149
            :..|:..|.:.|   :.......||:|.|..:           .:.:|.|.::|.||.:|.|:..
plant    99 LREGDPTFREELLNFSQRGRILQLSNFKDDSS-----------PIAWDCSAWVRTYALFLEERLE 152

  Fly   150 SYRAMAFD-----FCKVKRGKEEG--SLRSMNAEKLLKTLPVLQAQLDALLEFDCQSNDLS--NG 205
            .:|.:.:|     ..|...|:::|  ..|.::.|:||:.||.||..|..|:  .|:....:  |.
plant   153 CFRVLKYDTEAERLPKSNPGQDKGYSRTRDLDGEELLEQLPALQQLLYRLI--GCRPEGAANHNH 215

  Fly   206 VINMSFMLLFRDLIRLFACYNDGIINLLEKYFDMNKKHARDALDLYKKFLVRMDRVGEFLKVAEN 270
            ||..:..|:.::..:::...|||||||::|:|:|.|..|..:|::||:...:...:.:|.:..:.
plant   216 VIQYALALVLKESFKVYCAINDGIINLIDKFFEMAKHEAITSLEIYKRAGQQARSLSDFYEACKG 280

  Fly   271 VGIDKG-DIPDLTKAPSSLLDALEQHLATLEGRKVSAANTP---------------TQSSSNQRN 319
            :.:.:. ..|.|.:.|.|.|..:|:::.... |.|.....|               |:.|..:|.
plant   281 LELARNFQFPVLREPPQSFLTTMEEYIKEAP-RVVDVPAEPLLLTYRPDDGLTTEDTEPSHEERE 344

  Fly   320 VKSAVSALSSTSSAFGTAAASSKFDTTNGIDEQLKAQVLAEEEAAMNQYKSKVSSPTSSGAAGAS 384
            :..:...:                             |::||
plant   345 MLPSDDVV-----------------------------VVSEE----------------------- 357

  Fly   385 AALTNPFLSSPPAAQAGQPIV---DLFGAASAQP-----------AAAAAATKASDDLLQLGNPF 435
               |.|....||:|.| |..:   ||:|..:..|           |.|..:|.|.......|.|
plant   358 ---TEPSPPPPPSANA-QNFIDTDDLWGLNTGAPDTSVIEDQNALALAIVSTDADPPTPHFGQP- 417

  Fly   436 ADMFDASGGGAAAVGATGF------------------------NGASVSS------AAATNAFVS 470
             :.:|.:|...|.|.|...                        :||.::|      |.|.|.|.|
plant   418 -NNYDPTGWELALVTAPSSDISASTERKLAGGLDTLTLSSLYDDGAYIASQRPVYGAPAPNPFAS 481

  Fly   471 DSNFSSVFGNTEPAASTSLPNPF--------------FDDMSLPQIPLPAESVAAPFGNNINFMD 521
            ...|:|..|...|....::.|||              :...|.|    |..: :.|||:...|..
plant   482 HDPFASSNGTAPPPQQQAVNNPFGAYQQTYQHQPQPTYQHQSNP----PTNN-SNPFGDFGEFPV 541

  Fly   522 QQLQQQQQAALY 533
            ..:.||...:.|
plant   542 NPVSQQPNTSGY 553

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lap	NP_001163538.1	ANTH	21..298	CDD:284961	76/287 (26%)
lap	NP_001163538.1	Amelogenin	694..>773	CDD:197891
AT2G01600	NP_565267.1	ANTH	29..310	CDD:284961	76/288 (26%)
AT2G01600	NP_565267.1	YppG	467..>517	CDD:290883	12/49 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	111	1.000	Domainoid score	I2074
eggNOG	1	0.900	-	-		E1_KOG0251
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	115	1.000	Inparanoid score	I2025
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22951
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X389
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	8	7.920