Protein Alignment CG10055 and SHQ1

DIOPT Version :10

• Sequence 1: NP_649703.1
• Gene: CG10055 / 40862
• FlyBaseID: FBgn0037482
• Length: 608
• Species: Drosophila melanogaster
• Sequence 2: NP_060600.2
• Gene: SHQ1 / 55164
• HGNCID: 25543
• Length: 577
• Species: Homo sapiens
• Alignment Length: 600
• Identity: 142/600 - (23%)
• Similarity: 236/600 - (39%)
• Gaps: 165/600 - (27%)

  Fly    66 RIRNCDIFVDAHDLYFYADVKLYKFHSRRTFDLR-ELKTLLIKFNTTENHYQ-----ICLRCLPL 124
            |:...|::.:..|..|||          :.:.|| .|...:::..:.:..|.     ..:| ||
Human    25 RVSEFDVYFEGSDFKFYA----------KPYFLRLTLPGRIVENGSEQGSYDADKGIFTIR-LP- 77

  Fly   125 TAGAQEGPGGERGGGGGTGDAAKQWNSRKEYIAAFLHLPTLSANL-PDK----QPLVQEWKLKRI 184
                :|.||..                       |..|..|:|.| |.|    :|||:|.....|
Human    78 ----KETPGQH-----------------------FEGLNMLTALLAPRKSRTAKPLVEEIGASEI 115

  Fly   185 TDQCQLQLDDHERTYK-------------LTNNFGYGYASEYSGPL-----DLSELDRATCRVSE 231
            .::.   :||.|..::             |.....||:.:..||.|     :||::    ..:.:
Human   116 PEEV---VDDEEFDWEIEQTPCEEVSESALNPQCHYGFGNLRSGVLQRLQDELSDV----IDIKD 173

  Fly   232 PHRMSPIQRRQERVVDEMKRFSREQYKINFVELQVPSGHQNPLRYKP----------KIYETSMT 286
            |......:|||:|:..|:.:|..:.|..:|.|   ....:..|:|.|          ...|.|..
Human   174 PDFTPAAERRQKRLAAELAKFDPDHYLADFFE---DEAIEQILKYNPWWTDKYSKMMAFLEKSQE 235

  Fly   287 QEQAHLLHNIS---RMQTR---------EQQPCDVFRQNEIDCGLISILLAICYDVRTTNNEPTC 339
            ||....|.:.|   :.|.|         :::.|     .::...||.||||.||:.|.|..|...
Human   236 QENHATLVSFSEEEKYQLRKFVNKSYLLDKRAC-----RQVCYSLIDILLAYCYETRVTEGEKNV 295

  Fly   340 ESGWTRSILCPLYCYFEQFDNYRDVLVAFLRRMITYPLYRNFELGRQCVRDAIEVLKGGRNWLIN 404
            ||.|....|.|..|:||.:.|..|::|:|.||::.|||||:|:|..:..||.|::|:.|::.::.
Human   296 ESAWNIRKLSPTLCWFETWTNVHDIMVSFGRRVLCYPLYRHFKLVMKAYRDTIKILQLGKSAVLK 360

  Fly   405 QLLLTHQQFASSDPSRDSFNNYYLEDYIRYVTSPSACSDEHMRLLARNLKNVLMDVNKQHLGLGV 469
            .||..|:.|..:||:. ..|:.|:.||..::   .....:.:..||..||.|  .:.|..|||.:
Human   361 CLLDIHKIFQENDPAY-ILNDLYISDYCVWI---QKVKSKKLAALAEALKEV--SLTKAQLGLEL 419

  Fly   470 TEIETELIKELMQEMRIDAGSQGSSPQQQHGDDDLDLDNDTSGQEDETTTDDESVITDSFYSVDM 534
            .|:|...:  |:||                .:..|...:..|||:...::.:.|
Human   420 EELEAAAL--LVQE----------------EETALKAAHSVSGQQTLCSSSEAS----------- 455

  Fly   535 DMRLIENEIVYEDDEEDEDDD-EDGDDDEDGDGDEDEDEDEDE-----------DDSSSSTTTSS 587
                         |.||.|.. ..|::|...|.::||.:|...           ::||:......
Human   456 -------------DSEDSDSSVSSGNEDSGSDSEQDELKDSPSETVSSLQGPFLEESSAFLIVDG 507

  Fly   588 EAEGNSVIEQCSNSE 602
            ....|:.|::...|:
Human   508 GVRRNTAIQESDASQ 522

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10055	NP_649703.1	SHQ1	312..467	CDD:461483	54/154 (35%)
SHQ1	NP_060600.2	SHQ1	234..412	CDD:461483	59/188 (31%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	447..492		11/68 (16%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	549..577