DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sas and CCN6

DIOPT Version :9

Sequence 1:	NP_001262337.1	Gene:	sas / 40861	FlyBaseID:	FBgn0002306	Length:	1693	Species:	Drosophila melanogaster
Sequence 2:	NP_003871.1	Gene:	CCN6 / 8838	HGNCID:	12771	Length:	354	Species:	Homo sapiens

Alignment Length:	400	Identity:	81/400 - (20%)
Similarity:	113/400 - (28%)	Gaps:	148/400 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly   596 CCRVMECSEPQLEPTVVATEGAAPSTNGTGESAVTLPTTDD------EATPKPRTDCHYNSGVYK 654
            ||||                      .|||    .|.||.:      ...|:.:..||:.
Human    18 CCRV----------------------QGTG----PLDTTPEGRPGEVSDAPQRKQFCHWP----- 51

  Fly   655 FRERLEIGCEQICHCAEGGVMDCRPRCPERNHTRLDKC----VYVKDPKDVCCQLELCDVTLDDH 715
                        |.|.:.     :||||.......|.|    :..|.|.::|.:.:||
Human    52 ------------CKCPQQ-----KPRCPPGVSLVRDGCGCCKICAKQPGEICNEADLC------- 92

  Fly   716 EQQPTPLQSNNNEDPEE-------IDPFRFQEQARDAGGAKPTCTFKGAEYDVGQQFRDGCDQLC 773
                         ||.:       :|..|: |....|......|.|....|..||.|:......|
Human    93 -------------DPHKGLYCDYSVDRPRY-ETGVCAYLVAVGCEFNQVHYHNGQVFQPNPLFSC 143

  Fly   774 ICNEQGIHCAKLECPSNFGLDVQDPHCIRWEPVPADFKPSPPNCCPESMRCVDNGTCSYQG---- 834
            :|....|.|..|..|...|     .||   .......|....||..|.:  :...:.||:.
Human   144 LCVSGAIGCTPLFIPKLAG-----SHC---SGAKGGKKSDQSNCSLEPL--LQQLSTSYKTMPAY 198

  Fly   835 ------------VQIENWSPVPANLTGCDQHCYC--------ENGRVECR---AACPPVPALPPA 876
                        ||...|:|       |.:.|..        ||...|.|   ..|        .
Human   199 RNLPLIWKKKCLVQATKWTP-------CSRTCGMGISNRVTNENSNCEMRKEKRLC--------Y 248

  Fly   877 DLPCHPALARLLPIPDDECCKHWMCAPQIPKIGGAGQDEETEATSTHSSIPANETTTTTATANKS 941
            ..||...:.:.:.||..:.|:......:..|...:|      .:||.|..|    |......:|.
Human   249 IQPCDSNILKTIKIPKGKTCQPTFQLSKAEKFVFSG------CSSTQSYKP----TFCGICLDKR 303

  Fly   942 TSIPSKVPQI 951
            ..||:|...|
Human   304 CCIPNKSKMI 313

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sas	NP_001262337.1	VWC	752..824	CDD:214564	19/71 (27%)
		fn3	1413..1479	CDD:278470
		FN3	1516..1605	CDD:238020
CCN6	NP_003871.1	IGFBP	48..100	CDD:365955	17/93 (18%)
CCN6	NP_003871.1	GHB_like	275..341	CDD:389804	11/48 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11348
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.100