DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sas and ccn6

DIOPT Version :9

Sequence 1:	NP_001262337.1	Gene:	sas / 40861	FlyBaseID:	FBgn0002306	Length:	1693	Species:	Drosophila melanogaster
Sequence 2:	NP_001159703.1	Gene:	ccn6 / 794092	ZFINID:	ZDB-GENE-041001-86	Length:	338	Species:	Danio rerio

Alignment Length:	322	Identity:	67/322 - (20%)
Similarity:	104/322 - (32%)	Gaps:	99/322 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   663 CEQICHCAEGGVMDCRPRCPERNHTRLDKC----VYVKDPKDVCCQLELCD----VTLDDHEQQP 719
            |...|.|   ||   ||.|.....:.||.|    ...:...:.|.:.::||    :..|..:.||
Zfish    34 CSWPCKC---GV---RPLCAPGVSSILDGCGCCKTCAQQIGESCNERDICDPHKSMYCDFSKDQP 92

  Fly   720 TPLQSNNNEDPEEIDPFRFQ----EQARDAGGAKPTCTFKGAEYDVGQQFRDGCDQLCICNEQGI 780
                             |::    ......|     |...||.||.||.|:......|.|....|
Zfish    93 -----------------RYEVGICAYLMGVG-----CDLNGAHYDNGQAFQPNPLYKCTCISGSI 135

  Fly   781 HC--AKLECPSNFGLDVQDPHCIRWEPVPADFKPS--PPNCCPESMRCVDNGTCSYQG------- 834
            .|  |.::.|:.    :..|..::.: :||..|.|  |.|....:.|.:.    :|:.
Zfish   136 GCTPAFIQKPTG----MLSPAALQGQ-LPAGLKSSRNPKNQQDTTYRTMS----AYRDPPLAWKK 191

  Fly   835 ---VQIENWSPVPANLTGCDQHC------YCENGRVEC-----RAACPPVPALPPADLPCHPALA 885
               ||...|||       |.:.|      ...|...:|     |..|        ...||.....
Zfish   192 NCLVQTTAWSP-------CSRSCGIGISVRVNNDNSKCEMRKERRLC--------LLRPCDKNTL 241

  Fly   886 RLLPIPDDECCKHWMCAPQIPKIGGAGQDEETEATSTHSSIPANETTTTTATANKSTSIPSK 947
            :.|.:|..:.||....|.:..|:..:|          .:|:..:..|......:|...:|:|
Zfish   242 KRLKMPKGKTCKPKFQASKAEKLSLSG----------CTSVKKHRPTYCGVCTDKRCCVPNK 293

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sas	NP_001262337.1	VWC	752..824	CDD:214564	21/75 (28%)
		fn3	1413..1479	CDD:278470
		FN3	1516..1605	CDD:238020
ccn6	NP_001159703.1	IGFBP	34..79	CDD:278641	13/50 (26%)
ccn6	NP_001159703.1	GHB_like	259..326	CDD:304424	7/45 (16%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11348
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.100