DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sas and Ccn4

DIOPT Version :9

Sequence 1:	NP_001262337.1	Gene:	sas / 40861	FlyBaseID:	FBgn0002306	Length:	1693	Species:	Drosophila melanogaster
Sequence 2:	NP_113904.2	Gene:	Ccn4 / 65154	RGDID:	69431	Length:	367	Species:	Rattus norvegicus

Alignment Length:	264	Identity:	54/264 - (20%)
Similarity:	75/264 - (28%)	Gaps:	91/264 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   663 CEQICHCAEGGVMDCRPRCPERNHTRLDKCVYVKDPKDVCCQLELCDVTLDDHEQQPTPLQSNNN 727
            |:..|.|.:     ..||||.......|.|        .||  ::|...|.|           |.
  Rat    49 CKWPCECPQ-----APPRCPLGVSLITDGC--------ECC--KICAQQLGD-----------NC 87

  Fly   728 EDPEEIDPFRFQEQARDAGGAKPT-------------CTFKGAEYDVGQQFRDGCDQLCICNEQG 779
            .:....||.|  ....|..|.:|.             |...|..|..|:.|:..|...|.|.:..
  Rat    88 TEAAVCDPHR--GLYCDYSGDRPRYAIGVCAQVVGVGCVLDGVRYTNGESFQPNCRYNCTCIDGT 150

  Fly   780 IHCAKLEC--PSNFGLDVQDPHCIRWEPVPADFKPSPPNCC-----------PESMRCVDNGTCS 831
            :.|..| |  |....|..:.|..:|          .|..||           |.....:|....:
  Rat   151 VGCTPL-CLSPRPPRLWCRQPRHVR----------VPGQCCEQWVCDDDARRPRQTALLDTRAFA 204

  Fly   832 YQGV---QIEN-------WSP--------VPANLTGCDQHCYCENGRVECRAACPPVPALPPADL 878
            ..|.   :.||       |||        :...::..:..|:.|.....|.        |.|.|:
  Rat   205 ASGAVEQRYENCIAYTSPWSPCSTTCGLGISTRISNVNARCWPEQESRLCN--------LRPCDV 261

  Fly   879 PCHP 882
            ...|
  Rat   262 DIRP 265

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sas	NP_001262337.1	VWC	752..824	CDD:214564	19/84 (23%)
		fn3	1413..1479	CDD:278470
		FN3	1516..1605	CDD:238020
Ccn4	NP_113904.2	IGFBP	49..101	CDD:395164	18/79 (23%)
		VWC	123..181	CDD:214564	17/68 (25%)
		TSP1_CCN	216..259	CDD:408805	7/50 (14%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11348
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100