DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sas and ccn4a

DIOPT Version :9

Sequence 1:	NP_001262337.1	Gene:	sas / 40861	FlyBaseID:	FBgn0002306	Length:	1693	Species:	Drosophila melanogaster
Sequence 2:	NP_001159702.1	Gene:	ccn4a / 560713	ZFINID:	ZDB-GENE-070705-178	Length:	360	Species:	Danio rerio

Alignment Length:	414	Identity:	71/414 - (17%)
Similarity:	121/414 - (29%)	Gaps:	160/414 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly   504 TSTTTTTAQPETEMPKIVEITASGDTMQRECLANNKSYKHGELMERDCDERCTCNRGDWMCEPRC 568
            :|...:|.:|.|..|                 .|...|         |...|.|.:...||.|
Zfish    25 SSNLLSTEEPITPQP-----------------YNRSQY---------CQWPCKCPKTPPMCPP-- 61

  Fly   569 RGLSYPRGSQRSMANPNCLEKMVEEDECCRVMECSEPQLEPTVVATEGAAPSTNGTGESAVTLPT 633
             |:|.                :::..:|||.  |::.       ..|......|......:..
Zfish    62 -GVSL----------------LMDGCDCCRA--CAKQ-------VREACNEKENCDHHRGLYC-- 98

  Fly   634 TDDEATPKPR-----------TDCHYNSGVYKFRERLEIGCEQICHCAEGGVMDCRPRCPERNHT 687
              |.:..|||           |.|.:|..:|:..:..:..|:..|.|..|.: .|.|.|.|....
Zfish    99 --DYSADKPRYEKGVCAFLPGTGCEHNGVIYRNGQSFQPNCKYQCLCVNGAI-GCVPLCNESQPP 160

  Fly   688 RLDKCVYVKDPKDV-----CCQLELCDVTLDDHEQQP-------------------------TPL 722
            |    |:.::|:.|     ||:|.:||.:....:..|                         :|.
Zfish   161 R----VWCQNPQRVKVHGQCCELWICDESRRGRKTAPRHTMAALSSVKKNWHKNCVAQTTSWSPC 221

  Fly   723 Q-----------SNNNEDPEEIDPFRFQEQARDAGGAKPTCTFKGAEYDVGQQFRDGCDQLCICN 776
            .           :|||:..|.::..|.             |..:....|:.:..:.|
Zfish   222 SKTCGRGVSLRITNNNKKCEMVNESRL-------------CNIRPCNVDITKHIKPG-------- 265

  Fly   777 EQGIHCAKLECPSNFGLDVQDPHCIRWEPVPADFKPSPPNCCPESMRCVDNGTCSYQGVQIE--- 838
            ::.::..:.|.|.||.:.    .|....    .::|.....|.:...|:     .|:...||
Zfish   266 KKCLNIYRAEKPQNFTIS----GCTSTN----TYRPKYCGVCTDERCCI-----PYKSKTIEVDF 317

  Fly   839 --------NWSPVPANLTGCDQHC 854
                    .|..:..|...|:..|
Zfish   318 QCPNGPGFTWQVMWINACFCNLSC 341

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sas	NP_001262337.1	VWC	752..824	CDD:214564	10/71 (14%)
		fn3	1413..1479	CDD:278470
		FN3	1516..1605	CDD:238020
ccn4a	NP_001159702.1	IGFBP	46..98	CDD:278641	14/79 (18%)
		VWC	120..178	CDD:214564	16/62 (26%)
		GHB_like	275..341	CDD:304424	14/78 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11348
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.100