DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment sas and Ccn6

DIOPT Version :9

Sequence 1:	NP_001262337.1	Gene:	sas / 40861	FlyBaseID:	FBgn0002306	Length:	1693	Species:	Drosophila melanogaster
Sequence 2:	NP_001163954.1	Gene:	Ccn6 / 499461	RGDID:	1564120	Length:	354	Species:	Rattus norvegicus

Alignment Length:	421	Identity:	85/421 - (20%)
Similarity:	119/421 - (28%)	Gaps:	164/421 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly   596 CCRVMECSEPQLEPTVVATEGAAPSTNGTGESAVTLPTTDDEATPKPRTDCHYNSGVYKFRERLE 660
            |||......|          ||.|.    |:....|.                   ||:.:|
  Rat    18 CCRAQGSVPP----------GATPG----GQPGAALE-------------------VYQRKE--- 46

  Fly   661 IGCEQICHCAEGGVMDCR-----PRCPERNHTRLDKC----VYVKDPKDVCCQLELCDVTLDDHE 716
                 :||      ..||     |.||.......|.|    :..|.|.|:|.:.|.|
  Rat    47 -----VCH------WPCRCPPQVPTCPPGVSLVRDGCGCCKICAKQPGDICNEAESC-------- 92

  Fly   717 QQPTPLQSNNNEDPEEIDPFR--FQEQARDAGGAKPT-------------CTFKGAEYDVGQQFR 766
                             ||.:  :.:.:||    ||.             |.|.|..|..||.|:
  Rat    93 -----------------DPHKGLYCDYSRD----KPRYETGVCAYLVAVGCEFNGVHYQNGQVFQ 136

  Fly   767 DGCDQLCICNEQGIHCAKL--------ECPS-NFGLDVQDPHCIRWEP----------VPADFKP 812
            ......|:|....|.|..|        .|.| ..|..:..|.|.:..|          :|| ::.
  Rat   137 PHPLFSCLCVSGAIGCTPLFRPKLAGSNCSSARGGRKIDPPDCGQGSPQQGRSAGYRTMPA-YRN 200

  Fly   813 SPPNCCPESMRCVDNGTCSYQGVQIENWSP--------VPANLTGCDQHCYCENGRVECRAACPP 869
            .||..   ..:|:         ||...|:|        :...:|..:.:|...|.:..|...
  Rat   201 LPPTW---KKKCL---------VQATRWTPCSRTCGMGISNRVTNDNSNCEMRNEKRLCYIQ--- 250

  Fly   870 VPALPPADLPCHPALARLLPIPDDECCKHWMCAPQIPKIGGAGQDEETEATSTHSSIPANETTTT 934
                     ||.....:...||..|.|:...   |:||       .|....|..||......|..
  Rat   251 ---------PCGRKPWKAGKIPRGETCQPTF---QLPK-------AEKFVFSGCSSAQTYRPTFC 296

  Fly   935 TATANKSTSIPSKVPQIKKDEEKRPPASGAF 965
            ....:|...:|:|...|....:  .|..|:|
  Rat   297 GICLDKRCCVPNKSTMITVRFD--CPGEGSF 325

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sas	NP_001262337.1	VWC	752..824	CDD:214564	22/90 (24%)
		fn3	1413..1479	CDD:278470
		FN3	1516..1605	CDD:238020
Ccn6	NP_001163954.1	IGFBP	48..100	CDD:278641	17/82 (21%)
Ccn6	NP_001163954.1	GHB_like	275..342	CDD:304424	14/60 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11348
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100