DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sas and CCN3

DIOPT Version :9

Sequence 1:	NP_001262337.1	Gene:	sas / 40861	FlyBaseID:	FBgn0002306	Length:	1693	Species:	Drosophila melanogaster
Sequence 2:	NP_002505.1	Gene:	CCN3 / 4856	HGNCID:	7885	Length:	357	Species:	Homo sapiens

Alignment Length:	206	Identity:	55/206 - (26%)
Similarity:	79/206 - (38%)	Gaps:	48/206 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   750 PTCTFKGAEYDVGQQFRDGCDQLCIC-NEQGIHCAKLE-CPSNFGLDVQDPHCIRWEPVPADFKP 812
            |||. .|.     :...|||....:| .::|..|:.|| |..:.||     :|        |...
Human    48 PTCA-PGV-----RAVLDGCSCCLVCARQRGESCSDLEPCDESSGL-----YC--------DRSA 93

  Fly   813 SPPN---CCPESMRCVDNGTCSYQGV---QIENWSPVPANLTGCDQHCYCENGRVECRAACPPVP 871
            .|.|   .|    ..|:...|.:.||   ..|.:.|      .|...|.|.:|::.|...|....
Human    94 DPSNQTGIC----TAVEGDNCVFDGVIYRSGEKFQP------SCKFQCTCRDGQIGCVPRCQLDV 148

  Fly   872 ALPPADLPCHPALARLLPIPDDECCKHWMCAP-QIPKIGG----AGQDEETEATS-THSSIPANE 930
            .||..:.|.    .|.:.:| .|||:.|:|.| :...:||    |.:.|.|.... :.||:...|
Human   149 LLPEPNCPA----PRKVEVP-GECCEKWICGPDEEDSLGGLTLAAYRPEATLGVEVSDSSVNCIE 208

  Fly   931 TTTTTATANKS 941
            .||.....:||
Human   209 QTTEWTACSKS 219

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sas	NP_001262337.1	VWC	752..824	CDD:214564	18/76 (24%)
		fn3	1413..1479	CDD:278470
		FN3	1516..1605	CDD:238020
CCN3	NP_002505.1	IB	33..>95	CDD:197525	17/65 (26%)
		VWC	110..170	CDD:214564	19/70 (27%)
		CT	269..338	CDD:214482
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11348
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.100