DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sas and Ccn6

DIOPT Version :9

Sequence 1:	NP_001262337.1	Gene:	sas / 40861	FlyBaseID:	FBgn0002306	Length:	1693	Species:	Drosophila melanogaster
Sequence 2:	NP_001120848.1	Gene:	Ccn6 / 327743	MGIID:	2685581	Length:	354	Species:	Mus musculus

Alignment Length:	413	Identity:	86/413 - (20%)
Similarity:	122/413 - (29%)	Gaps:	148/413 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly   596 CCRVMECSEPQLEPTVVATEGAAPSTNGTGESAVTLPTTDDEATPKPRTDCHYNSGVYKFRERLE 660
            |||               |:|:||                .::||..|......  ||   :|.|
Mouse    18 CCR---------------TQGSAP----------------QDSTPGGRPGAALE--VY---QRTE 46

  Fly   661 IGCEQICHCAEGGVMDCRPRCPERNHTRLDKC----VYVKDPKDVCCQLELCDVTLDDHEQQPTP 721
            : |...|.|...     ||.||.......|.|    |..|.|.|.|.:.|:|    |.|:....
Mouse    47 V-CRWPCRCPPQ-----RPTCPPGVSLVRDGCGCCKVCAKQPGDTCNEAEIC----DPHKGLYC- 100

  Fly   722 LQSNNNEDPEEIDPFRFQEQARDAGGAKPT-------------CTFKGAEYDVGQQFRDGCDQLC 773
                                  |..|..|.             |.|....|..||.|:......|
Mouse   101 ----------------------DYSGDTPRYETGVCAYLVAVGCEFNRVYYQNGQVFQPHPLFSC 143

  Fly   774 ICNEQGIHCAKLECPSNFGLDVQDPHCIRWEPVPADFKPSPPNCCPESMRCVDNGTCSYQG---- 834
            :|....|.|..|..|...|.:.......|        |..||||...:::  ...:.||:.
Mouse   144 LCVSGAIGCTPLFIPKLAGSNCSAAKGRR--------KTDPPNCGRGTLQ--QQNSASYKTMSAY 198

  Fly   835 ------------VQIENWSP--------VPANLTGCDQHCYCENGRVECRAACPPVPALPPADLP 879
                        ||...|:|        :...:|..:.:|.....|..|...            |
Mouse   199 RNLPLTWRKKCLVQATKWTPCSRTCGMGISNRVTNDNANCEMRKERRLCYIQ------------P 251

  Fly   880 CHPALARLLPIPDDECCKHWMCAPQIPKIGGAGQDEETEATSTHSSIPANETTTTTATANKSTSI 944
            |....::.:.||..|.|:.....|:..|...:|      .:||.|..|    |......:|...:
Mouse   252 CSRNTSQAVKIPRGETCQPTFQLPKAEKFVFSG------CSSTQSYRP----TFCGICLDKRCCV 306

  Fly   945 P--SKVPQIKKDEEKRPPASGAF 965
            |  ||:..::.|    .|:.|:|
Mouse   307 PNKSKMITVRFD----CPSEGSF 325

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sas	NP_001262337.1	VWC	752..824	CDD:214564	19/71 (27%)
		fn3	1413..1479	CDD:278470
		FN3	1516..1605	CDD:238020
Ccn6	NP_001120848.1	IGFBP	48..100	CDD:395164	18/60 (30%)
		TSP1_CCN	209..252	CDD:408805	8/54 (15%)
		GHB_like	275..341	CDD:419725	16/65 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11348
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100