DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sas and Ccn5

DIOPT Version :9

Sequence 1:	NP_001262337.1	Gene:	sas / 40861	FlyBaseID:	FBgn0002306	Length:	1693	Species:	Drosophila melanogaster
Sequence 2:	NP_113778.2	Gene:	Ccn5 / 29576	RGDID:	621867	Length:	250	Species:	Rattus norvegicus

Alignment Length:	277	Identity:	68/277 - (24%)
Similarity:	93/277 - (33%)	Gaps:	118/277 - (42%)

- Green bases have known domain annotations that are detailed below.

  Fly   659 LEIGCEQICH--CAEGGVMDC---RPRCPERNHTRLDKCVYVKDPKDVCCQL------ELCD-VT 711
            |.:.|.|:|.  |.      |   .|:||:.....||.|        .||::      |.|| :.
  Rat    18 LSMVCAQLCRTPCT------CPWTPPQCPQGVPLVLDGC--------GCCKVCARRLGESCDHLH 68

  Fly   712 LDDHEQ----QPTPLQSNNNEDPEEIDPFRFQEQARDAGGAKP--------------TCTFKGAE 758
            :.|..|    ||                           ||.|              :|...|..
  Rat    69 VCDPSQGLVCQP---------------------------GAGPGGHGAVCLLDEDDGSCEVNGRR 106

  Fly   759 YDVGQQFRDGCDQLCICNEQGIHCAKLECPSNFGLDVQDPHCIRWE-PVPADFKPSPPNCCPESM 822
            |..|:.|:..|..||.|::.|..|..| |..    ||:.|   .|: |.|...: .|..||||.:
  Rat   107 YLDGETFKPNCRVLCRCDDGGFTCLPL-CSE----DVRLP---SWDCPRPKRIQ-VPGRCCPEWV 162

  Fly   823 RCVDNGT------CSYQGVQIE-------------NWSPV--PANLTGC---------DQHCYCE 857
             | |.|.      .:.||.|:.             |||..  |.:.| |         :|:.:|:
  Rat   163 -C-DQGVTPAIQRSTAQGHQLSALVTPASADAPCPNWSTAWGPCSTT-CGLGIATRVSNQNRFCQ 224

  Fly   858 NGRVEC-RAACPPVPAL 873
               :|. |..|.|.|.|
  Rat   225 ---LEIQRRLCLPRPCL 238

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sas	NP_001262337.1	VWC	752..824	CDD:214564	24/72 (33%)
		fn3	1413..1479	CDD:278470
		FN3	1516..1605	CDD:238020
Ccn5	NP_113778.2	IGFBP	26..78	CDD:395164	16/65 (25%)
		VWC	100..159	CDD:327433	21/67 (31%)
		TSP1_CCN	194..237	CDD:408805	12/46 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11348
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100