DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sas and Ccn5

DIOPT Version :9

Sequence 1:	NP_001262337.1	Gene:	sas / 40861	FlyBaseID:	FBgn0002306	Length:	1693	Species:	Drosophila melanogaster
Sequence 2:	NP_058569.2	Gene:	Ccn5 / 22403	MGIID:	1328326	Length:	251	Species:	Mus musculus

Alignment Length:	252	Identity:	61/252 - (24%)
Similarity:	79/252 - (31%)	Gaps:	88/252 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   663 CEQICHCAEGGVMDCRPRCPERNHTRLDKCVYVKDPKDVCCQL------ELCD-VTLDDHEQ--- 717
            |...|.|..     ..|:||......||.|        .||::      |.|| :.:.|..|
Mouse    26 CPAPCACPW-----TPPQCPPGVPLVLDGC--------GCCRVCARRLGESCDHLHVCDPSQGLV 77

  Fly   718 -QPTPLQSNNNEDPEEIDPFRFQEQARDAGGAKPTCTFKGAEYDVGQQFRDGCDQLCICNEQGIH 781
             ||....|....      ...|:|   |.|    :|...|..|..|:.|:..|..||.|::.|..
Mouse    78 CQPGAGPSGRGA------VCLFEE---DDG----SCEVNGRRYLDGETFKPNCRVLCRCDDGGFT 129

  Fly   782 CAKLECPSNFGLDVQDPHCIRWE-PVPADFKPSPPNCCPESMRCVDNGTCSYQGVQIENWSPVPA 845
            |..| |..    ||:.|   .|: |.|...: .|..||||                   |.
Mouse   130 CLPL-CSE----DVRLP---SWDCPRPRRIQ-VPGRCCPE-------------------WV---- 162

  Fly   846 NLTGCDQHCYCENGRVECRAACPPVPALPPADLPCHPALARLLPIPDDECCKHWMCA 902
                |||              ....||:.|:....|...|.:.|...|..|.:|..|
Mouse   163 ----CDQ--------------AVMQPAIQPSSAQGHQLSALVTPASADGPCPNWSTA 201

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sas	NP_001262337.1	VWC	752..824	CDD:214564	24/72 (33%)
		fn3	1413..1479	CDD:278470
		FN3	1516..1605	CDD:238020
Ccn5	NP_058569.2	IGFBP	26..78	CDD:278641	16/64 (25%)
Ccn5	NP_058569.2	VWC	100..159	CDD:214564	21/67 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11348
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100