DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sas and Ccn4

DIOPT Version :9

Sequence 1:	NP_001262337.1	Gene:	sas / 40861	FlyBaseID:	FBgn0002306	Length:	1693	Species:	Drosophila melanogaster
Sequence 2:	NP_061353.1	Gene:	Ccn4 / 22402	MGIID:	1197008	Length:	367	Species:	Mus musculus

Alignment Length:	378	Identity:	77/378 - (20%)
Similarity:	107/378 - (28%)	Gaps:	119/378 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   618 APSTNGTGESAVTLPTTDDEATPKPRTDCHYNSGVYKFRERLEIGCEQICHCAEGGVMDCRPRCP 682
            |.:.:.|..:....|...:|.|.:|..                  |:..|.|.:.     .||||
Mouse    22 ATALSPTPTTMTFTPAPLEETTTRPEF------------------CKWPCECPQS-----PPRCP 63

  Fly   683 ERNHTRLDKCVYVKDPKDVCCQLELCDVTLDDHEQQPTPLQSNNNEDPEEIDPFRFQEQARDAGG 747
            .......|.|        .||  ::|...|.|           |..:....||.|  ....|..|
Mouse    64 LGVSLITDGC--------ECC--KICAQQLGD-----------NCTEAAICDPHR--GLYCDYSG 105

  Fly   748 AKPT-------------CTFKGAEYDVGQQFRDGCDQLCICNEQGIHCAKLECPSNFGLDVQDPH 799
            .:|.             |...|..|..|:.|:..|...|.|.:..:.|.              |.
Mouse   106 DRPRYAIGVCAQVVGVGCVLDGVRYTNGESFQPNCRYNCTCIDGTVGCT--------------PL 156

  Fly   800 CIRWEPVPADFKPSPPNC-CPESMRCVDNGTCSYQGVQIENWSPVPANLTGCDQHCYCENGRVE- 862
            |:         .|.||.. |.:.......|.|..|.| .::.:..|......|...:..:|.||
Mouse   157 CL---------SPRPPRLWCRQPRHVRVPGQCCEQWV-CDDDARRPRQTALLDTRAFAASGAVEQ 211

  Fly   863 ----CRAACPPVPALPPADLPCHPAL--------ARLLPIPDDECCKHWMCAPQIPKIGGAG--- 912
                |.|...|   ..|....|...:        ||..|..:...|....|...|.....||
Mouse   212 RYENCIAYTSP---WSPCSTTCGLGISTRISNVNARCWPEQESRLCNLRPCDVDIQLHIKAGKKC 273

  Fly   913 ----QDEETEATSTHSSIPANETTTT-------TATANKSTSIPSKVPQIKKD 954
                |.||    :|:.::....:|.|       ..|.|: ..||.|...|..|
Mouse   274 LAVYQPEE----ATNFTLAGCVSTRTYRPKYCGVCTDNR-CCIPYKSKTISVD 321

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sas	NP_001262337.1	VWC	752..824	CDD:214564	15/72 (21%)
		fn3	1413..1479	CDD:278470
		FN3	1516..1605	CDD:238020
Ccn4	NP_061353.1	IGFBP	49..101	CDD:278641	18/79 (23%)
		VWC	123..181	CDD:214564	17/80 (21%)
		TSP_1	220..259	CDD:301595	7/41 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11348
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100