DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sas and ccn5

DIOPT Version :9

Sequence 1:	NP_001262337.1	Gene:	sas / 40861	FlyBaseID:	FBgn0002306	Length:	1693	Species:	Drosophila melanogaster
Sequence 2:	NP_001186030.1	Gene:	ccn5 / 100007759	ZFINID:	ZDB-GENE-060223-1	Length:	344	Species:	Danio rerio

Alignment Length:	285	Identity:	60/285 - (21%)
Similarity:	87/285 - (30%)	Gaps:	113/285 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly   660 EIGCEQI---CHCAEGGVMDCRPRCPERNHTRLDKCVYVKDPKDVCCQLELCDVTLDDHEQQPTP 721
            ::.|:|.   |.| :|.|    |.|||.....||.|        .|||  :|
Zfish    25 QVCCQQCGSSCQC-QGSV----PSCPEGVPLILDGC--------QCCQ--VC------------- 61

  Fly   722 LQSNNNEDPEEIDPFRFQEQARDAGGAKPTCTFKGAEYDVGQQFRDGCDQLCICN-EQGIHCAKL 785
                                ||..|                    :.|.::..|: ::|:.|
Zfish    62 --------------------ARQQG--------------------EACSEVFPCDGQRGLQC--- 83

  Fly   786 ECPSNFGLDVQDPHCIRWEPVPADFKPSPPNCCPE-SMRCVDNGTCSYQGVQIENWSPVPANLTG 849
                               ...|.|...|..|..: .:.|..||. |||..|:  :.|      .
Zfish    84 -------------------DYSASFPGEPGECVSQKELGCELNGV-SYQEGQV--FQP------S 120

  Fly   850 CDQHCYCENGRVECRAACPPVPALPPADLPCHPALARLLPIPDDECCKHWMCAPQIPKIGGAGQD 914
            |...|.|..|.|.|...|.....||..|.| ||...:    |..:|||.|:|    ..:......
Zfish   121 CSLQCQCSGGGVTCVPQCREDVLLPTPDCP-HPRRVQ----PPGKCCKEWVC----ENLDNTVLQ 176

  Fly   915 EETEATSTHSSIPANETTTTTATAN 939
            :...|:.:..::||:....|...:|
Zfish   177 DAHIASKSDLTLPADSGYQTRVVSN 201

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sas	NP_001262337.1	VWC	752..824	CDD:214564	8/73 (11%)
		fn3	1413..1479	CDD:278470
		FN3	1516..1605	CDD:238020
ccn5	NP_001186030.1	IGFBP	31..83	CDD:278641	21/119 (18%)
		VWC	104..163	CDD:214564	23/72 (32%)
		GHB_like	266..334	CDD:304424
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11348
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.100