DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MAGE and Maged2

DIOPT Version :9

Sequence 1:	NP_649702.2	Gene:	MAGE / 40860	FlyBaseID:	FBgn0037481	Length:	232	Species:	Drosophila melanogaster
Sequence 2:	NP_001186175.1	Gene:	Maged2 / 80884	MGIID:	1933391	Length:	616	Species:	Mus musculus

Alignment Length:	238	Identity:	68/238 - (28%)
Similarity:	112/238 - (47%)	Gaps:	31/238 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 RAARSQNAIPSQEAQQP----VDVVDAKVRAILNYILDHTAQKIPIKDKDLIAVAGDKSELKKRL 66
            |||:.|:   |||.:.|    |.::..:...::.|:|.....||||:..|::     |..:|:..
Mouse   258 RAAKLQS---SQEPEAPPPRDVALLQGRANDLVKYLLAKDQTKIPIRRSDML-----KDIIKEYT 314

  Fly    67 PLVTNL-------LAETFGIILTPLDATTKTFI--CTAEEPVASIHELTPAQRPQFTLLYIILMY 122
            .:...:       |.:.|||.|..:|.....:|  .|.|...|.|.. |....|:..||.::|..
Mouse   315 DVYPEIIERAGYSLEKVFGIQLKEIDKNDHLYILLSTLEPTDAGILG-TTKDSPKLGLLMVLLSI 378

  Fly   123 IFLRGNRIEDSKLYVMLEMLNIYPDEEHGYFGPNLRKQIEETFVKQQYLKRER---SQLSAYDDS 184
            ||:.|||..::.::.:|..|.:.|...|..|| :::|.|.:.||||:||...|   |....|:
Mouse   379 IFMNGNRSSEAVIWEVLRKLGLRPGIHHSLFG-DVKKLITDEFVKQKYLDYARVPNSNPPEYE-- 440

  Fly   185 KTFFLWGPRAKAEFTFEQMVQFASKLLNQHPKVFGHHLSMAQE 227
               |.||.|:..|.:..::::||.|:..:.||.:......|.|
Mouse   441 ---FFWGLRSYYETSKMKVLKFACKVQKKDPKEWAAQYREAME 480

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MAGE	NP_649702.2	MAGE	36..201	CDD:279759	52/176 (30%)
Maged2	NP_001186175.1	PRK13335	32..>125	CDD:139494
		PRK13914	<33..224	CDD:237555
		MAGE	286..454	CDD:366651	52/179 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167842086
Domainoid	1	1.000	53	1.000	Domainoid score	I11275
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1195799at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm42492
orthoMCL	1	0.900	-	-		OOG6_105159
Panther	1	1.100	-	-	LDO	PTHR11736
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.850