DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MAGE and nsmce3

DIOPT Version :9

Sequence 1:	NP_649702.2	Gene:	MAGE / 40860	FlyBaseID:	FBgn0037481	Length:	232	Species:	Drosophila melanogaster
Sequence 2:	XP_012809679.1	Gene:	nsmce3 / 549684	XenbaseID:	XB-GENE-1007635	Length:	260	Species:	Xenopus tropicalis

Alignment Length:	243	Identity:	77/243 - (31%)
Similarity:	117/243 - (48%)	Gaps:	43/243 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 STSRAARS-QNAIPSQEAQQPVDVVDAKVRAILNYILDHTAQKIPIKDKDLI--AVAGDKS---E 61
            |.|:|.|: ||  .|||.      ::.||..::.|:|....:|:|||..|::  .|...|.   |
Frog    36 SLSQAQRNLQN--HSQEQ------INLKVGEVVQYLLIKDQKKLPIKRADIVRNVVKEYKDIYPE 92

  Fly    62 LKKRLPLVTNLLAETFGIILTPLDATTKTFICTAEEPVASIHELTPAQRPQ------------FT 114
            :.:|..:.   |.:.||..|..:|..:..:|.|           ...||.|            ..
Frog    93 IFRRAQIA---LQQVFGFQLEEIDTKSHIYILT-----------NKLQRVQGDGMRVDENTSKLG 143

  Fly   115 LLYIILMYIFLRGNRIEDSKLYVMLEMLNIYPDEEHGYFGPNLRKQIEETFVKQQYLKRERSQLS 179
            ||.:||..||::||..::|.::.||..|.|.|.|:|..|| :::|.|.|.||||:||  |.|::.
Frog   144 LLMVILSLIFMKGNTAKESAVWEMLRRLRIEPAEKHSDFG-DVKKLITEEFVKQKYL--EYSKVL 205

  Fly   180 AYDDSKTFFLWGPRAKAEFTFEQMVQFASKLLNQHPKVFGHHLSMAQE 227
            ..|..:..|.||.||..|.:..|:::|.||:..:.||.:......|||
Frog   206 HTDPVEYEFRWGQRAFKETSKMQVLEFVSKIQQKDPKSWTTQYKDAQE 253

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MAGE	NP_649702.2	MAGE	36..201	CDD:279759	57/181 (31%)
nsmce3	XP_012809679.1	MAGE	59..227	CDD:366651	57/184 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	87	1.000	Inparanoid score	I4992
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1195799at2759
OrthoFinder	1	1.000	-	-		FOG0000171
OrthoInspector	1	1.000	-	-		oto102439
Panther	1	1.100	-	-	LDO	PTHR11736
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2068
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	6.190