DRSC/TRiP Functional Genomics Resources

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Protein Alignment MAGE and MAGEL2

DIOPT Version :9

Sequence 1:NP_649702.2 Gene:MAGE / 40860 FlyBaseID:FBgn0037481 Length:232 Species:Drosophila melanogaster
Sequence 2:NP_061939.3 Gene:MAGEL2 / 54551 HGNCID:6814 Length:1249 Species:Homo sapiens


Alignment Length:230 Identity:64/230 - (27%)
Similarity:110/230 - (47%) Gaps:25/230 - (10%)


- Green bases have known domain annotations that are detailed below.


  Fly     3 STSRAARSQNAIPSQEAQQPVDVVDAKVRAILNYILDHTAQKIPIKDKDLIAV--AGDKSELKKR 65
            |...:|...|   |:...||:..:|.:..|::.::|.....|:|::..:::.|  ...|.|....
Human  1000 SPGSSATQDN---SKVEAQPLSPLDERANALVQFLLVKDQAKVPVQRSEMVKVILREYKDECLDI 1061

  Fly    66 LPLVTNLLAETFGIILTPLDATTKTFICTAE------EPVASIHELTPAQRPQFTLLYIILMYIF 124
            :....|.|...||..|..:|.....:|...:      ..|||.     ..||:|.||.::|..||
Human  1062 INRANNKLECAFGYQLKEIDTKNHAYIIINKLGYHTGNLVASY-----LDRPKFGLLMVVLSLIF 1121

  Fly   125 LRGNRIEDSKLYVMLEMLNIYPDEEHGYFGPNLRKQIEETFVKQQYLKRER---SQLSAYDDSKT 186
            ::||.:.:..::..|..|.:...|.:|.|| |.:|.|.|.||:|:||:..|   ::.:.|:    
Human  1122 MKGNCVREDLIFNFLFKLGLDVRETNGLFG-NTKKLITEVFVRQKYLEYRRIPYTEPAEYE---- 1181

  Fly   187 FFLWGPRAKAEFTFEQMVQFASKLLNQHPKVFGHH 221
             |||||||..|.:...:::|.:||..:.|:.:..|
Human  1182 -FLWGPRAFLETSKMLVLRFLAKLHKKDPQSWPFH 1215

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
MAGENP_649702.2 MAGE 36..201 CDD:279759 51/175 (29%)
MAGEL2NP_061939.3 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..50
Drf_FH1 82..235 CDD:283903
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 134..233
WWbp <135..206 CDD:304964
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 300..327
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 349..378
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 410..433
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 515..569
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 647..679
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 714..746
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 862..910
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 930..957
MAGE 1027..1195 CDD:279759 51/178 (29%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1226..1249
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C165151971
Domainoid 1 1.000 63 1.000 Domainoid score I10231
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1195799at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR11736
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
54.950

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