Protein Alignment MAGE and MAGEA3

DIOPT Version :9

• Sequence 1: NP_649702.2
• Gene: MAGE / 40860
• FlyBaseID: FBgn0037481
• Length: 232
• Species: Drosophila melanogaster
• Sequence 2: NP_005353.1
• Gene: MAGEA3 / 4102
• HGNCID: 6801
• Length: 314
• Species: Homo sapiens
• Alignment Length: 235
• Identity: 52/235 - (22%)
• Similarity: 104/235 - (44%)
• Gaps: 35/235 - (14%)

  Fly     3 STSRAARSQNAIPSQEAQQPVDVVDAKVRAILNYILDHTAQKIPIKDKDLI-AVAGD-------- 58
            |:::.....:..|..|::... .:..||..:::::|.....:.|:...::: :|.|:
Human    87 SSNQEEEGPSTFPDLESEFQA-ALSRKVAELVHFLLLKYRAREPVTKAEMLGSVVGNWQYFFPVI 150

  Fly    59 KSELKKRLPLVTNLLAETFGIILTPLDATTKTFI---C--TAEEPVASIHELTPAQRPQFTLLYI 118
            .|:....|.||       |||.|..:|.....:|   |  .:.:.:...:::    .|:..||.|
Human   151 FSKASSSLQLV-------FGIELMEVDPIGHLYIFATCLGLSYDGLLGDNQI----MPKAGLLII 204

  Fly   119 ILMYIFLRGNRIEDSKLYVMLEMLNIYPDEEHGYFGPNLRKQIEETFVKQQYLKRERSQLSAYDD 183
            :|..|...|:...:.|::..|.:|.::...|....| :.:|.:.:.||::.||  |..|:...|.
Human   205 VLAIIAREGDCAPEEKIWEELSVLEVFEGREDSILG-DPKKLLTQHFVQENYL--EYRQVPGSDP 266

  Fly   184 SKTFFLWGPRAKAEFTFEQMVQFASKLLNQHPKVFGHHLS 223
            :...|||||||..|.::.:::....|:..      |.|:|
Human   267 ACYEFLWGPRALVETSYVKVLHHMVKISG------GPHIS 300

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MAGE	NP_649702.2	MAGE	36..201	CDD:279759	43/178 (24%)
MAGEA3	NP_005353.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..99		1/11 (9%)
		MAGE_N	5..94	CDD:289225	1/6 (17%)
		MAGE	116..280	CDD:279759	42/177 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165151962
Domainoid	1	1.000	63	1.000	Domainoid score	I10231
eggNOG	1	0.900	-	-		E1_KOG4562
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	92	1.000	Inparanoid score	I5087
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1195799at2759
OrthoFinder	1	1.000	-	-		FOG0000171
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11736
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	9	8.900