DRSC/TRiP Functional Genomics Resources

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Protein Alignment MAGE and Magel2

DIOPT Version :9

Sequence 1:NP_649702.2 Gene:MAGE / 40860 FlyBaseID:FBgn0037481 Length:232 Species:Drosophila melanogaster
Sequence 2:NP_038807.4 Gene:Magel2 / 27385 MGIID:1351648 Length:1284 Species:Mus musculus


Alignment Length:222 Identity:59/222 - (26%)
Similarity:107/222 - (48%) Gaps:13/222 - (5%)


- Green bases have known domain annotations that are detailed below.


  Fly     3 STSRAARSQNAIPSQEAQQPVDVVDAKVRAILNYILDHTAQKIPIKDKDLIAVA-----GDKSEL 62
            |.||.:.:....|.:|: ||:..:|.:..|::.::|.....|:|::..:::.|.     .|..::
Mouse  1030 SVSRGSSAAQEDPDRES-QPLSPLDERANALVQFLLVKDQAKVPVQLSEMVNVVIREYKDDSLDI 1093

  Fly    63 KKRLPLVTNLLAETFGIILTPLDATTKTFICTAEEPVASIHELTP-AQRPQFTLLYIILMYIFLR 126
            ..|   ....|..|||..|..:|..|.|:|...:......:.|.. .:||:|:||.::|..||::
Mouse  1094 INR---ANTKLECTFGCQLKEVDTKTHTYIIVNKMAYPQCNLLASYLERPKFSLLMVVLSLIFMK 1155

  Fly   127 GNRIEDSKLYVMLEMLNIYPDEEHGYFGPNLRKQIEETFVKQQYLKRERSQLSAYDDSKTFFLWG 191
            |..|.::.|:..|..|.:...|..|.|... :|.|...||:.:||  |..|:...:.::...|||
Mouse  1156 GYCIRENLLFSFLFQLGLDVQETSGLFRIT-KKLITSVFVRHRYL--EYRQIPFTEPAEYELLWG 1217

  Fly   192 PRAKAEFTFEQMVQFASKLLNQHPKVF 218
            |||..|.....:::|.:.|....|:::
Mouse  1218 PRAFLETNRVHILRFLAALYENQPQIW 1244

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
MAGENP_649702.2 MAGE 36..201 CDD:279759 47/170 (28%)
Magel2NP_038807.4 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..51
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 114..208
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 406..431
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 673..717
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 747..792
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 839..860
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 913..964
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 985..1051 7/21 (33%)
MAGE 1059..1223 CDD:279759 46/169 (27%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1261..1284
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C167842088
Domainoid 1 1.000 53 1.000 Domainoid score I11275
eggNOG 1 0.900 - - E1_KOG4562
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1195799at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 1 1.000 - - otm42492
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR11736
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 1 0.960 - -
87.810

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