Protein Alignment Sas-4 and Cenpj

DIOPT Version :9

• Sequence 1: NP_649701.2
• Gene: Sas-4 / 40859
• FlyBaseID: FBgn0011020
• Length: 901
• Species: Drosophila melanogaster
• Sequence 2: NP_001382046.1
• Gene: Cenpj / 305909
• RGDID: 1310464
• Length: 1344
• Species: Rattus norvegicus
• Alignment Length: 1142
• Identity: 273/1142 - (23%)
• Similarity: 453/1142 - (39%)
• Gaps: 354/1142 - (30%)

  Fly    24 ALSRWQ------DEQKRLLQERQSNHRVLLGLEQRNMYKMLGLLHQETESHENSVLEEWD-EEHS 81
            ||..|:      .|.|.:..:|..:...::.:|:|   .:...:.::.::.|:.:.|:.. ||..
  Rat   288 ALPCWEKKMGKSQEGKDVNLQRSRDSSGVVNIEER---PIKAAIREKQQTFEDYLEEQIRLEERE 349

  Fly    82 IQMPRLAADPDEHEPEISMADPQPAKPKRPFLRRGEGLKQRFKINPDQLRLENLPRYKFANAHPQ 146
            ::..:|   .:...|.::     ..|||:|||:|||||.                  :|.||..:
  Rat   350 LRQKQL---QEAEGPLLT-----KMKPKQPFLKRGEGLA------------------RFTNAKCK 388

  Fly   147 FRTPQMKKGILKKQVKSPPNPAPPPAPKPSAQLDDLNEQRFQQ--MLIGKNACSSTPDLKSSYAS 209
            |     :||   |:.|.    |...:|.....:..::.|..|:  .||.::.|:.|..:|....:
  Rat   389 F-----QKG---KESKL----ASTQSPSEQQSVPKVDRQHLQRKTALINRDLCADTTSVKKDSKA 441

  Fly   210 STTASSTSPRVRFVEQKSRAGQTTHAD----------------------------------DEAS 240
            .:.|.|.|.|     ||.:..:|...|                                  :...
  Rat   442 RSKAGSASLR-----QKPKVTKTNRRDSLSPPGRKVQTGKKCDGQFRPQVKLERNVPTNNKENVP 501

  Fly   241 SEASPMTGVC--WAKV-------LDT--------QSIKPAQIQRRSAQI------------RVED 276
            :...|....|  |.|.       |.|        :|:.|...::..:.:            |.::
  Rat   502 AYIKPWGAGCKVWNKTQGRDRLPLSTGPVGCVVSRSLVPETDRQTESSLDISLQKKLENWEREKE 566

  Fly   277 DSNVSI--FELLEQKATEGNIDMNSSCIRTFMAR------------------KDQRRRVAD---D 318
            ..|:.:  |..||:.|.|.:...|||.:...:.|                  :.|:.:.||   .
  Rat   567 KENLELDEFLFLERAADEISFSSNSSFVLKILERDQQIYEGHRLSSTPVKAVQPQKAQQADPWGQ 631

  Fly   319 SDHIVVTQQ-----------------------VRQM--RLQPQVDQMLVQELQ------EGDEED 352
            |:|..|.:.                       :|::  :|..:..|....|.|      :||..:
  Rat   632 SNHSEVPRPSVAHEDESEFEAMLLSRGSGSPGLRELSCKLSKKAFQNSTSENQGRWDAGDGDVAN 696

  Fly   353 TEPSS---DQTLTMTPIQVGNTKVRVRFSDSNDTHEYSDA------------------------- 389
            ::.||   :..:|:.|......:|   ||:..|:.:..||
  Rat   697 SDSSSESEEHDITIKPSTEAEDRV---FSNREDSPQVCDAKGPSRDTGAQEDQWRDADLDLSDKE 758

  Fly   390 ----------------------TSLNDGSNIQLFEQFKSALFQALEQ------------------ 414
                                  .|.:|||.:. |:..:|  :..||:
  Rat   759 CSSDESVTVESLSSQVLEPLRLPSSHDGSKVD-FDDERS--WADLEENPHEHGVVPREEAMSGTS 820

  Fly   415 -----------------KKKSSPSKESDE---------PITKDLQEK------------------ 435
                             |:|.:|.|:.::         |...||..|
  Rat   821 QTHCHSTSEGCVLDKTIKRKIAPVKKGEDFSKSDRSVSPPPSDLMVKFFPSLKPKPKLDSHVENE 885

  Fly   436 ----------------ANLVRTRLEELETEIATFKEQNAQLLRLRQQHELEKAKCTQDHMEAMER 484
                            :.::|.::.|||:||..||.:|..|.:||.:.|....|..::..:..::
  Rat   886 PKLSLSQDQPPGDSVRSQVLREKVIELESEIEKFKAENTSLAKLRIERESALEKLRKEIADFEQQ 950

  Fly   485 VHDEKIQAEIYLHDERMKIEEERRKFEQQMRLQKSNANSKEKKEIAALKQEVEGLQLQLKQKEQA 549
            ...|..:.|.|..:|..|:::||:.||:.....::..:.||::||.||||:::.||..||:||..
  Rat   951 KARELARIEEYKKEETRKLQKERKVFEKYTAAARTFPDKKEREEIQALKQQIQELQEDLKRKETK 1015

  Fly   550 HVSAQARLRAQLRASEKEQRNYRDEIELLRKENKRLEQELVKIGRENNSKMLQEINRNIARLAPK 614
            ..|...|||:|:....||..:.|:||:::  |..|||........||:.|..|.|      :|.|
  Rat  1016 WSSTHGRLRSQIEMLVKENTDLREEIKVM--ERFRLEAWKRAEAIENSPKACQYI------MATK 1072

  Fly   615 VLPSATMSDILDENGRRTQSLDGTAGKPAKQREAQNRRQSSGSAQVRSRS---RSLSRNKKTPYA 676
            ...|...|    ...:::.:..|..|:..|::..    .:.|::..||:|   |.|....|...|
  Rat  1073 KDESMNSS----IQFQKSHASLGVQGEKYKKKYL----PAQGNSSRRSKSVPPRDLGSLDKGQAA 1129

  Fly   677 L-----------DESYASSSSVESEEVQPPVTAPKAATPPPAANSSSDFKREITNADGSKDIWYP 730
            |           |..|.:....| ||:|..:..|             |.|.|....:|.:.:.:|
  Rat  1130 LPREPLQPVNFPDLEYKNKEEKE-EEIQGEINHP-------------DGKVEKVYKNGCRVVLFP 1180

  Fly   731 NGNLKKISADGMNLRMLYFNKDIKETNIREGTVKYYYAETNTWHTSYLDGLEILEFPNGQTEHRR 795
            ||..|::||||.::.:.:||.|:|:. :.:..|.||||...|.||:|.:|||:|.|.:||.|...
  Rat  1181 NGTRKEVSADGKSITVTFFNGDVKQV-MPDERVVYYYAAAQTTHTTYPEGLEVLHFSSGQIEKHF 1244

  Fly   796 KDGTVEIHFPNNSIKIVDPSDTEKLEEWRYADGTHLVQLRNGDKILNLPNGQKEIHTKLNKRREY 860
            .||..||.||:.:||.:   ..:..||..:.|||.:...|:|:||:...|||:|:||...|||||
  Rat  1245 PDGRKEITFPDQTIKTL---FADGQEESIFPDGTIVRVQRDGNKIIEFNNGQRELHTAQFKRREY 1306

  Fly   861 PDGTVKLVYPDGSQETRYSNGRVRLKDKDGKLIMDTD 897
            ||||||.||.:|.|||:|::||||:|||||.::|||:
  Rat  1307 PDGTVKTVYANGHQETKYTSGRVRVKDKDGNVLMDTE 1343

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sas-4	NP_649701.2	DUF2570	<517..>587	CDD:305162	27/69 (39%)
		Tcp10_C	717..895	CDD:284589	81/177 (46%)
Cenpj	NP_001382046.1	Smc	<901..>1046	CDD:224117	47/146 (32%)
		Tcp10_C	1158..1187	CDD:399882	9/41 (22%)
		Tcp10_C	1227..1260	CDD:399882	15/32 (47%)
		Tcp10_C	1264..1297	CDD:399882	13/32 (41%)
		Tcp10_C	1301..1331	CDD:399882	21/29 (72%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166353367
Domainoid	1	1.000	159	1.000	Domainoid score	I3989
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	267	1.000	Inparanoid score	I2958
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm45848
orthoMCL	1	0.900	-	-		OOG6_105142
Panther	1	1.100	-	-	LDO	PTHR10331
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X6202
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	9.890