Protein Alignment Sas-4 and LOC1281228

DIOPT Version :10

• Sequence 1: NP_649701.2
• Gene: Sas-4 / 40859
• FlyBaseID: FBgn0011020
• Length: 901
• Species: Drosophila melanogaster
• Sequence 2: XP_061500494.1
• Gene: LOC1281228 / 1281228
• VectorBaseID: AGAMI1_007622
• Length: 1075
• Species: Anopheles gambiae
• Alignment Length: 1094
• Identity: 371/1094 - (33%)
• Similarity: 539/1094 - (49%)
• Gaps: 237/1094 - (21%)

  Fly    14 SQEAIAQRLAALSRWQDEQKRLLQERQSNHRVLLGLEQRNMYKMLGLLHQETES------HENSV 72
            |..:|..||..|.:||:||:|:|.|:....:.||..||:.||::|||.....::      .|.|.
Mosquito     4 SPRSILVRLEQLKQWQEEQQRVLLEKHLAQQQLLEREQQKMYQVLGLRQHSLDNAGDDGGGEESY 68

  Fly    73 LEEWDEEHSIQMPRLAA---------------------DPDEHEPEISMADP-QPAK--PKRPFL 113
            .|: |.|...:...|.|                     |.:..:|....|.. |..|  ||:.||
Mosquito    69 AED-DSEPEYEETNLQAQLASERLQQQAASGRDDTTVFDSENEQPTAEQAQALQKTKNVPKKRFL 132

  Fly   114 RRGEGLKQRFKINPDQLRLENLPRYKFANAHPQFRT------------------PQMKKGILKKQ 160
            :|||||:.|||::||:.:|||||:||||| |.:.|:                  |:..:....||
Mosquito   133 KRGEGLRARFKVDPDKFKLENLPKYKFAN-HNRERSNRKGEPRQQQSDGVSSSAPKASRASGSKQ 196

  Fly   161 VKSPPNPAPPPAPKPSAQLD-----DLNEQRFQQMLIGKNACSSTPDLKSSYASSTTASSTSPRV 220
            .|....| ||...|...:.|     |:|..:.::::..:....|.|.:.:.  ::|..:.|:...
Mosquito   197 GKVEVKP-PPVEKKLRNKSDQGIVLDINRVQDKKLISTRRMGGSLPTINAE--ATTQDAHTNETD 258

  Fly   221 RFVEQKSRAGQTTHADDEASSEASPMTGVCWAKVLDTQSIKPAQIQRRSAQIRVEDDSNVSIFEL 285
            :.:..:.:....|...::...:......:.|.|.|    :.||...:.|.:.|     :::.|||
Mosquito   259 QMLADRVKRFSVTDMIEKIVEKPPAKPNLPWKKRL----LDPAVPPKVSKEQR-----DLNFFEL 314

  Fly   286 LEQKATEGNIDMNSSCIRTFMARKD----QRRRVADDSDH---IVVTQQVRQM------RLQPQV 337
            ||:|....|...|||.|..|:|..:    :.....|:|.:   ...|..|||.      ||.|..
Mosquito   315 LEKKVVGKNFSPNSSSILRFIAANESTANEETLTNDESMYEPTATGTALVRQEEVIVKDRLSPPP 379

  Fly   338 DQMLVQELQEGDE--------------------EDTEPSSDQT------LTMTPIQVGNTKVRVR 376
            .:..::| .:.||                    |||:.:..:|      :|.:.:...|.|:..|
Mosquito   380 SRADLKE-DDSDESDDDRAHVHFAEDGSKCSAGEDTDVTEHETYHRMQRITSSKMSTPNDKMITR 443

  Fly   377 FSDSNDTHEYSDATSLNDGSNIQLFEQFKSALFQALEQKKKSSPSKES----------------- 424
                :::||.:...|.:|... :..|:.|....:..|.......:.:|
Mosquito   444 ----SESHEQTGQASESDEEE-EEDEEEKGRTKECAEDDDDDDATVDSANGQSETEDTTVAGVNV 503

  Fly   425 DEPITKDLQEKANLVRTRLEELETEIATFKEQNAQLLRLRQQHELEKAKCTQDHMEAMERVHDEK 489
            |:.:..::..|:.|::.||.|||.||..::.:||:|::.:|:||||:.|..|:..|..|.::||:
Mosquito   504 DDTLRSEILAKSELLKQRLTELEREIDNYRRENAELIQAKQEHELERLKLQQEREELEEHMNDER 568

  Fly   490 IQAEIYLHDERMKIEEERRKFEQQMRLQKSNANSKEKKEIAALKQEVEGLQLQLKQKEQAHVSAQ 554
            |:.|:|.||||||||.||:   |.:| :....|.|:::||..|.:|:..::.|.|::|..|.::.
Mosquito   569 IKMEVYFHDERMKIETERK---QALR-EAQKPNKKDREEILRLNEELAEMRKQQKEREAKHSASL 629

  Fly   555 ARLRAQLRASEKEQRNYRDEIELLRKENKRLEQELVKIGRENNSKMLQEINRNIARLAP-KVLPS 618
            ||.||||:..:||.:..|.|:|:.:|:|:|||.|..::.|:|||:||.|||||||:||. ...|:
Mosquito   630 ARFRAQLKTVDKELQEVRLELEVAKKDNRRLETENTRLKRQNNSRMLVEINRNIAKLAAGGTEPA 694

  Fly   619 ATMSDILDENGRRTQ--SLDGTAGKPAKQREAQNRRQSSGSAQV-----------------RSRS 664
            |...:..:.|....|  |..|......|.::....:.|..|.||                 |:::
Mosquito   695 AERQESKEVNAAAAQDKSKRGLQPNRPKTQQVGESKVSKASVQVARAKVTSHPPMRGKVTMRTKA 759

  Fly   665 ----------------------------------RSLSRNKKT------------PYALDESYAS 683
                                              |.::.||.|            ..|:.|:  |
Mosquito   760 VRIQEQQEGLSSETDENNGNRFYAQHDSSDDDSDRPVNGNKSTEDEGDDDDDEDDDEAIGEN--S 822

  Fly   684 SSSVESEEVQ-------PPVTA---------PKAATP--------------------PPAANSSS 712
            ||:.:|..||       |.|..         ...|.|                    |.||....
Mosquito   823 SSAQDSSAVQSSYFPKNPAVRKTLFNAVNLNEDTAVPRQGLVRKENPLTQCDLLDRTPEAAEMIK 887

  Fly   713 DFKREITNADGSKDIWYPNGNLKKISADGMNLRMLYFNKDIKETNIREGTVKYYYAETNTWHTSY 777
            ..||||.|||||:||||||||||||||||:.:|||||||||||||:.|||.||||.|||||||:|
Mosquito   888 SMKREIVNADGSRDIWYPNGNLKKISADGLIIRMLYFNKDIKETNMTEGTTKYYYFETNTWHTTY 952

  Fly   778 LDGLEILEFPNGQTEHRRKDGTVEIHFPNNSIKIVDPSDTEKLEEWRYADGTHLVQLRNGDKILN 842
            ||||||||||:||||||.|||:.|:||||.||:..:|:..:..|||:|.|||.::..:|.||.:|
Mosquito   953 LDGLEILEFPDGQTEHRFKDGSTEVHFPNGSIRTTNPNSADIAEEWKYPDGTTVIIRKNDDKEIN 1017

  Fly   843 LPNGQKEIHTKLNKRREYPDGTVKLVYPDGSQETRYSNGRVRLKDKDGKLIMDT 896
            |||||.|||||.:|||.|||||||.||||||||:||||||:|||||||:||.||
Mosquito  1018 LPNGQVEIHTKAHKRRIYPDGTVKFVYPDGSQESRYSNGRIRLKDKDGRLISDT 1071

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sas-4	NP_649701.2	Smc	<435..>654	CDD:440809	87/221 (39%)
		YwqK	731..900	CDD:442097	122/166 (73%)
		Tcp10_C	821..850	CDD:462118	16/28 (57%)
		Tcp10_C	856..884	CDD:462118	24/27 (89%)
LOC1281228	XP_061500494.1	None