Protein Alignment Sas-4 and tcp10l2

DIOPT Version :9

• Sequence 1: NP_649701.2
• Gene: Sas-4 / 40859
• FlyBaseID: FBgn0011020
• Length: 901
• Species: Drosophila melanogaster
• Sequence 2: XP_012819173.2
• Gene: tcp10l2 / 100493055
• -ID: -
• Length: 1280
• Species: Xenopus tropicalis
• Alignment Length: 1171
• Identity: 281/1171 - (23%)
• Similarity: 452/1171 - (38%)
• Gaps: 336/1171 - (28%)

  Fly    12 PLSQEAIAQRLAALSRWQDEQKRLLQER--QSNHRVLLGLEQRNMYKMLGLLHQETESHENSVLE 74
            |:.:|..|.....|...:..|...:.|:  :.|||..:.:.  :|......:..|.......|.:
 Frog   157 PIGEEMSANNSVKLLNQECSQTGSVLEQLVEENHRDFMMIS--DMASSSTQISAEASKTLYLVEK 219

  Fly    75 EWDEEHSIQMP------RLAADPDEHEP-----------------EISMADPQPAKPK------- 109
            |.:||.|.|.|      ||.....|..|                 |...||.:.|:.|
 Frog   220 EKNEEPSTQTPLSPFGIRLKTKNHEERPLRPGIGVKQKTFEEFVEEQLKADSEFAQKKQSTESTF 284

  Fly   110 -------RPFLRRGEGLKQRFKINPDQL----RLENLPRY--------KFANAHPQFRTPQMKKG 155
                   :.||:||||: .||:..|..:    |..:||..        |..|:.|..........
 Frog   285 ERKASFRKSFLKRGEGI-TRFEKKPINMAKEERKHSLPNVSRSESFDSKHRNSLPSIHGEVKSCN 348

  Fly   156 ILKKQVKSPPNPAPPPAPKP-------SAQLDD-----LNEQRFQQMLIGKNA-CSSTPDLKSSY 207
            :.|::..|..|.....:..|       |.|.:|     ..:|.|....:.::. .||..:|:.|.
 Frog   349 LSKEKQASEENTNITLSDIPGTSDIMHSLQRNDKGKCLTEDQEFSHDTLQQHTRVSSEMELQYSS 413

  Fly   208 ASSTTASSTSPRVRFVEQKSRAGQTTHADDEASSEASPMTGVCWAKVLDTQSIKPAQIQRRSAQI 272
            ..:.|.|.|...:...|..:     .|....|:...||      ..|.:.:.||..:....:.::
 Frog   414 YYNPTLSKTETALSLHETNN-----AHKISIAAQPVSP------ESVANHEVIKEEKEPEENKKL 467

  Fly   273 R------VEDDSNVSIFELLEQKATEGNIDMNSSC--------IRTFMARKDQRRRVADDSDHIV 323
            .      :.:|.::.:|    :....|.|..::||        ::|...:.:.:...||....|:
 Frog   468 NSKKNSTLHNDLSLELF----KDTVLGTISEHNSCSAYTTDSSVKTGFKKLNDKIVPADPLGDIM 528

  Fly   324 VTQQ-----VRQMRLQP-------------------------QVDQMLVQ-----ELQEGDEEDT 353
            ..|:     |:..|::|                         .:.|.|.|     :|.:.|....
 Frog   529 EEQKFSVGTVQLKRVEPLSETDSVESNSDDDPKSPCYKLITHDIPQKLNQGDCHLDLSDPDYASD 593

  Fly   354 EPS--SDQTLTMTPIQVGNTKVRVRFSDSNDTHEYSDATSLNDGSNIQLFEQFKSALFQALE--Q 414
            |||  .|:.|.:....:.|.:   ..|:|:...|:...|....|:  :.|..|:...|:.|.  :
 Frog   594 EPSGEEDKKLHLPQKNMLNHQ---HPSESSSGSEHCKETFRRRGN--KAFSSFRKPSFRQLRMVR 653

  Fly   415 KKKSSPSKESD----------EPITKDLQEKANL-----VRTRLEELETEIATFKE---QNAQLL 461
            ::|....||.|          :|.|.||  .|||     ::..:.|....:....|   .|..|.
 Frog   654 QEKELNKKECDDSTKQSEPTFQPSTCDL--VANLFPVFKMKADIPECVAPLQKTSESHIDNPLLT 716

  Fly   462 RLRQQHELEKAKCTQDHMEAMERVHDEKI-QAEIYLHDERMKIEEERRKFEQQMRLQKSNANSKE 525
            :::::.|...|...| .:|..|:|..|:: :.|.:..:|..|:::|:...|:|..|.||...|::
 Frog   717 KMKEEQEKAMAFLRQ-QIEHFEKVKAEELKKMEEFKREEMKKLQKEKEDLEKQAALAKSIKESEQ 780

  Fly   526 KKEIAALKQEVEGLQLQLKQKEQAHVSAQARLRAQLRASEKEQRNYRDEIELLRKENKRLEQELV 590
            .:||..||.::..||.:..:.|....:.:.:|:.|              :|.|.:||:.|.:||
 Frog   781 NEEIQMLKLQISELQGEFHRHESRWSTTENQLKTQ--------------VETLTRENQELRKEL- 830

  Fly   591 KIGRENNSKMLQEINRNIARLAPKVLPSATMSDILDE----NGRRTQS---------LDGTAGK- 641
               |..:::.|:..|.....|..:.:...|.|.:.|:    |.|:::|         .|.:.||
 Frog   831 ---RAADNQFLEMQNYKSESLVSQAIMRGTSSSMADQRMGRNERKSRSSTPVERKTLYDLSYGKQ 892

  Fly   642 -----PAK-----------QREAQNRRQSSGSAQVRSRS----RSLSRNKKTPYALDE------- 679
                 .||           :|...|...||||.|.||.:    ::..|::.||:..|:
 Frog   893 PLPENSAKVNNLIERHDIIKRTGTNGDASSGSFQSRSGTPTGRKTPVRSRLTPFEPDKVTVVSAV 957

  Fly   680 -----------------------------SYASSS--------------------SVESEEVQPP 695
                                         ||:.||                    ::|.:|.:.|
 Frog   958 SHRKSPIPASHLSVFKESKISTQMKGRSSSYSGSSDDAPVSIIKNQELLHSSQSRNLERQESETP 1022

  Fly   696 -------------------VTAPKAATP------------------PP-----------AANSSS 712
                               .|..::.||                  .|           ..|.||
 Frog  1023 NIRKMQVQQSWEKQGVNTNKTRKRSVTPNGRKTPVDYTQCSEVKSSKPRSILSRKSSIHVGNKSS 1087

  Fly   713 ------------DFKREITNADGSKDIWYPNGNLKKISADGMNLRMLYFNKDIKETNIREGTVKY 765
                        |.|.|...:||...|.:.||..|:|||||....:|:||.|:|:. :.:.:|.|
 Frog  1088 EDESIQEETQYPDGKVEQLLSDGRTVISFSNGTKKEISADGKATTVLFFNGDVKKM-MPDQSVVY 1151

  Fly   766 YYAETNTWHTSYLDGLEILEFPNGQTEHRRKDGTVEIHFPNNSIKIVDPSDTEKLEEWRYADGTH 830
            ||||..|.||||..|||:|:|||.|.|....:|..||.||:.:||::   ..:..||..:.|||
 Frog  1152 YYAEAQTTHTSYPSGLEVLQFPNKQIEKHHPEGVKEIIFPDRTIKLL---YKDGREETTFPDGT- 1212

  Fly   831 LVQLR-NGDKILNLPNGQKEIHTKLNKRREYPDGTVKLVYPDGSQETRYSNGRVRLKDKDGKLIM 894
            :|:|. ||.|.:...||||||||...|||||||||:|.||.:|.|||:||:||||:||:.|.:|:
 Frog  1213 IVKLETNGMKTVIFHNGQKEIHTAQFKRREYPDGTIKTVYSNGRQETKYSSGRVRIKDQQGNIIL 1277

  Fly   895 D 895
            |
 Frog  1278 D 1278

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sas-4	NP_649701.2	DUF2570	<517..>587	CDD:305162	17/69 (25%)
		Tcp10_C	717..895	CDD:284589	88/178 (49%)
tcp10l2	XP_012819173.2	SMC_prok_B	<721..>870	CDD:274008	40/167 (24%)
		Tcp10_C	1090..1124	CDD:399882	9/33 (27%)
		Tcp10_C	1164..1196	CDD:399882	14/31 (45%)
		Tcp10_C	1200..1234	CDD:399882	15/34 (44%)
		Tcp10_C	1238..1268	CDD:399882	21/29 (72%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	162	1.000	Domainoid score	I3963
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0009891
OrthoInspector	1	1.000	-	-		oto104465
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6202
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.000