DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Sas-4 and cenpj

DIOPT Version :9

Sequence 1:NP_649701.2 Gene:Sas-4 / 40859 FlyBaseID:FBgn0011020 Length:901 Species:Drosophila melanogaster
Sequence 2:XP_031753132.1 Gene:cenpj / 100491003 XenbaseID:XB-GENE-1013036 Length:1597 Species:Xenopus tropicalis


Alignment Length:526 Identity:98/526 - (18%)
Similarity:172/526 - (32%) Gaps:147/526 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly   191 LIGKNACSSTPDLKSSYASSTTASSTSPRVRFVEQKSRAGQTTHADDEASSEASPMTGVCWAKVL 255
            :|.:|.|:....:........|......|:....|....|.|....            :.|....
 Frog   691 VIERNGCTEVEQILKDILHKNTVKLPVARINIAHQPGSGGSTVARQ------------ILWKYKN 743

  Fly   256 D------TQSIKPAQIQRRSAQIR----VEDDSNVSIFELLEQKATEGNID-------------- 296
            |      ..|...||:.....:.|    .|.:..:.:|.|||. ..|..||              
 Frog   744 DLRCAIVNSSYSVAQVCEHIIRFREYEEKEPNKCLPVFLLLED-CDEEYIDDLRHDLGEAMVYKK 807

  Fly   297 MNS--------SCIRTFMARKDQRRRVADDSDHIVVTQQVRQMRLQPQVDQMLVQELQEGDEEDT 353
            ||:        ||.|   :...|:...|...|.:.:|.::...      :|.|.:  .:.:|...
 Frog   808 MNNLKPRFILLSCKR---SNDPQKLCAASSHDTVAITHKLNSK------EQKLFK--AKAEELSA 861

  Fly   354 EPSSDQTLTMTPIQVGNTKVRVRFSDSNDTHEYSDATSLNDGSNIQLFEQFKSALFQALEQKKKS 418
            ..||:..:|...:..|..:..::....|..|:      ::..||:....::.:.|...::....|
 Frog   862 SFSSELIITFVLMSHGFEEKYLKDFVKNVMHD------IDHSSNVTRLIRYVALLNHYVQNSYIS 920

  Fly   419 SPSKE---SDEPITKDLQEKANLVRTRLEE---LETEIATFKEQNAQLLRLRQQHELEKAKCTQD 477
            ....|   ..:|..|:.|:|.||.:.:|::   |::......|:.::.......||..:.:....
 Frog   921 LSHCEEFLGIKPYLKESQQKDNLNKGKLKKQGRLKSSAKQHSEKGSETTSSVSDHEKSRMESLSQ 985

  Fly   478 H--------------MEAME--------RVHDEKIQAEI-------YLH--------DERMKI-- 503
            :              :|..|        |:....|..||       ||.        ||:..:  
 Frog   986 YNFVNSLNNQARLLFIELRESTTWISGIRILHPLIAEEILVQLPRTYLQSKIAMDLLDEKALLCH 1050

  Fly   504 ---EEERRKFEQQMRLQKSNANSKEKKEIAALKQEVEGLQLQLKQKEQAHVSAQARLRAQLRASE 565
               .|:..||.:|:.|::   :.|.:.:|      |:.....|.:    ||.             
 Frog  1051 RFAREDFVKFIRQLFLRR---HKKSRGDI------VDSFFSPLIE----HVC------------- 1089

  Fly   566 KEQRNYRDEIELLRKENKRLE------QELVKIGRENNSKMLQEINRNIARLAPKVLPSATMSDI 624
            |.:.|....|.||....:..:      |:|.:| ..||.|.  |..:..|..|...||:.  |.|
 Frog  1090 KAENNVEMAINLLEVAYEHFDKYPLFAQQLARI-HYNNEKF--EEAKKWAETAKAKLPND--SFI 1149

  Fly   625 LDENGR 630
            ||..|:
 Frog  1150 LDTEGQ 1155

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Sas-4NP_649701.2 DUF2570 <517..>587 CDD:305162 11/75 (15%)
Tcp10_C 717..895 CDD:284589
cenpjXP_031753132.1 SAM_superfamily 9..71 CDD:417767
TPR_19 1091..1147 CDD:405276 15/60 (25%)
TPR repeat 1112..1142 CDD:276809 9/32 (28%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 1 1.000 - -
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 1 1.100 - - LDO PTHR10331
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
33.010

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